node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DHFR-TS | DHFR-TS-2 | A0A4D8ZNA8 | A0A4D9C275 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | 0.999 |
DHFR-TS | Saspl_021048 | A0A4D8ZNA8 | A0A4D8ZXI4 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | GCV_T domain-containing protein. | 0.944 |
DHFR-TS | Saspl_021937 | A0A4D8ZNA8 | A0A4D9AAB0 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | GCV_T domain-containing protein. | 0.944 |
DHFR-TS | Saspl_032128 | A0A4D8ZNA8 | A0A4D8Z4F4 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Uncharacterized protein. | 0.951 |
DHFR-TS | gcvT | A0A4D8ZNA8 | A0A4D8ZDU2 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | 0.944 |
DHFR-TS | gcvT-2 | A0A4D8ZNA8 | A0A4D9AMD6 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Aminomethyltransferase. | 0.944 |
DHFR-TS | gcvT-3 | A0A4D8ZNA8 | A0A4D9ANJ3 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Aminomethyltransferase. | 0.944 |
DHFR-TS | purH | A0A4D8ZNA8 | A0A4D8YZF7 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | 0.973 |
DHFR-TS | purH-2 | A0A4D8ZNA8 | A0A4D8ZRR2 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | 0.973 |
DHFR-TS | purM | A0A4D8ZNA8 | A0A4D8Y0X2 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.998 |
DHFR-TS-2 | DHFR-TS | A0A4D9C275 | A0A4D8ZNA8 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | 0.999 |
DHFR-TS-2 | Saspl_021048 | A0A4D9C275 | A0A4D8ZXI4 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | GCV_T domain-containing protein. | 0.944 |
DHFR-TS-2 | Saspl_021937 | A0A4D9C275 | A0A4D9AAB0 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | GCV_T domain-containing protein. | 0.944 |
DHFR-TS-2 | Saspl_032128 | A0A4D9C275 | A0A4D8Z4F4 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Uncharacterized protein. | 0.951 |
DHFR-TS-2 | gcvT | A0A4D9C275 | A0A4D8ZDU2 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. | 0.944 |
DHFR-TS-2 | gcvT-2 | A0A4D9C275 | A0A4D9AMD6 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Aminomethyltransferase. | 0.944 |
DHFR-TS-2 | gcvT-3 | A0A4D9C275 | A0A4D9ANJ3 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Aminomethyltransferase. | 0.944 |
DHFR-TS-2 | purH | A0A4D9C275 | A0A4D8YZF7 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | 0.973 |
DHFR-TS-2 | purH-2 | A0A4D9C275 | A0A4D8ZRR2 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase. | 0.973 |
DHFR-TS-2 | purM | A0A4D9C275 | A0A4D8Y0X2 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.998 |