node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DHFR-TS | DHFR-TS-2 | A0A4D8ZNA8 | A0A4D9C275 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | 0.999 |
DHFR-TS | GAPDH | A0A4D8ZNA8 | A0A4D8XYR8 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.486 |
DHFR-TS | NR | A0A4D8ZNA8 | A0A4D8Y459 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria. | 0.583 |
DHFR-TS | NR-2 | A0A4D8ZNA8 | A0A4D8Z5B5 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria. | 0.583 |
DHFR-TS | NR-3 | A0A4D8ZNA8 | A0A4D8ZRF9 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Nitrate reductase (NAD(P)H). | 0.583 |
DHFR-TS | NR-4 | A0A4D8ZNA8 | A0A4D9BXA0 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Nitrate reductase (NAD(P)H). | 0.583 |
DHFR-TS | Saspl_009669 | A0A4D8ZNA8 | A0A4D9BCT0 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | NmrA domain-containing protein. | 0.707 |
DHFR-TS | tdk | A0A4D8ZNA8 | A0A4D8ZL32 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Thymidine kinase. | 0.997 |
DHFR-TS | tdk-2 | A0A4D8ZNA8 | A0A4D9ALQ2 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Thymidine kinase. | 0.997 |
DHFR-TS | tmk | A0A4D8ZNA8 | A0A4D8YU39 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | dTMP kinase. | 0.994 |
DHFR-TS-2 | DHFR-TS | A0A4D9C275 | A0A4D8ZNA8 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | 0.999 |
DHFR-TS-2 | GAPDH | A0A4D9C275 | A0A4D8XYR8 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Glyceraldehyde-3-phosphate dehydrogenase; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. | 0.486 |
DHFR-TS-2 | NR | A0A4D9C275 | A0A4D8Y459 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria. | 0.583 |
DHFR-TS-2 | NR-2 | A0A4D9C275 | A0A4D8Z5B5 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria. | 0.583 |
DHFR-TS-2 | NR-3 | A0A4D9C275 | A0A4D8ZRF9 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Nitrate reductase (NAD(P)H). | 0.583 |
DHFR-TS-2 | NR-4 | A0A4D9C275 | A0A4D9BXA0 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Nitrate reductase (NAD(P)H). | 0.583 |
DHFR-TS-2 | Saspl_009669 | A0A4D9C275 | A0A4D9BCT0 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | NmrA domain-containing protein. | 0.707 |
DHFR-TS-2 | tdk | A0A4D9C275 | A0A4D8ZL32 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Thymidine kinase. | 0.997 |
DHFR-TS-2 | tdk-2 | A0A4D9C275 | A0A4D9ALQ2 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | Thymidine kinase. | 0.997 |
DHFR-TS-2 | tmk | A0A4D9C275 | A0A4D8YU39 | Bifunctional dihydrofolate reductase-thymidylate synthase; Bifunctional enzyme. Involved in de novo dTMP biosynthesis. Key enzyme in folate metabolism; In the C-terminal section; belongs to the thymidylate synthase family. | dTMP kinase. | 0.994 |