htpX protein (Arthrobacter sp. ZXY2) - STRING interaction network

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Score

htpX

Protease; Belongs to the peptidase M48B family. (289 aa)

Predicted Functional Partners:

grpE

0.786

AOY73689.1

0.640

ftsH

0.545

AOY73784.1

0.545

AOY71743.1

0.544

entS

0.540

cysD

0.506

groES

0.503

aspS

0.491

dnaK

0.480

Your Current Organism:

Arthrobacter sp. ZXY2

NCBI taxonomy Id: 1806905
Other names: A. sp. ZXY-2, Arthrobacter sp. ZXY-2

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AOY71743.1	htpX	ARZXY2_2208	ARZXY2_625	Hypothetical protein.	Protease; Belongs to the peptidase M48B family.	0.544
AOY73689.1	htpX	ARZXY2_4189	ARZXY2_625	Histidine phosphatase; Belongs to the phosphoglycerate mutase family.	Protease; Belongs to the peptidase M48B family.	0.640
AOY73784.1	dnaK	ARZXY2_4284	ARZXY2_147	ATPase AAA; Belongs to the AAA ATPase family.	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.600
AOY73784.1	grpE	ARZXY2_4284	ARZXY2_148	ATPase AAA; Belongs to the AAA ATPase family.	Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]	0.404
AOY73784.1	htpX	ARZXY2_4284	ARZXY2_625	ATPase AAA; Belongs to the AAA ATPase family.	Protease; Belongs to the peptidase M48B family.	0.545
aspS	htpX	ARZXY2_1678	ARZXY2_625	aspartyl-tRNA synthase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.	Protease; Belongs to the peptidase M48B family.	0.491
cysD	htpX	ARZXY2_593	ARZXY2_625	Sulfate adenylyltransferase subunit 2.	Protease; Belongs to the peptidase M48B family.	0.506
dnaK	AOY73784.1	ARZXY2_147	ARZXY2_4284	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	ATPase AAA; Belongs to the AAA ATPase family.	0.600
dnaK	ftsH	ARZXY2_147	ARZXY2_3778	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	0.776
dnaK	groES	ARZXY2_147	ARZXY2_805	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Molecular chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.	0.903
dnaK	grpE	ARZXY2_147	ARZXY2_148	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]	0.999
dnaK	htpX	ARZXY2_147	ARZXY2_625	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	Protease; Belongs to the peptidase M48B family.	0.480
entS	htpX	ARZXY2_624	ARZXY2_625	MFS transporter.	Protease; Belongs to the peptidase M48B family.	0.540
ftsH	dnaK	ARZXY2_3778	ARZXY2_147	Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.776
ftsH	grpE	ARZXY2_3778	ARZXY2_148	Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]	0.404
ftsH	htpX	ARZXY2_3778	ARZXY2_625	Cell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.	Protease; Belongs to the peptidase M48B family.	0.545
groES	dnaK	ARZXY2_805	ARZXY2_147	Molecular chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.	Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.	0.903
groES	grpE	ARZXY2_805	ARZXY2_148	Molecular chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.	Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]	0.983
groES	htpX	ARZXY2_805	ARZXY2_625	Molecular chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.	Protease; Belongs to the peptidase M48B family.	0.503
grpE	AOY73784.1	ARZXY2_148	ARZXY2_4284	Molecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...]	ATPase AAA; Belongs to the AAA ATPase family.	0.404