STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KMO81293.1Exonuclease subunit SbcD. (382 aa)    
Predicted Functional Partners:
KMO81294.1
Chromosome segregation protein.
 
 0.999
uvrD2
ATP-dependent DNA helicase UvrD2.
  
 0.997
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.995
recQ
ATP-dependent DNA helicase RecQ.
  
 0.983
ypcP
5'-3' exonuclease.
   
 0.983
KMO75539.1
Hypothetical protein; Probable ATP-dependent helicase DinG homolog.
   
 0.979
recA
Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.975
topA
DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
 0.938
dauA
C4-dicarboxylic acid transporter DauA.
  
   0.920
petB
Cytochrome b6.
    
 
 0.896
Your Current Organism:
Mycolicibacterium obuense
NCBI taxonomy Id: 1807
Other names: ATCC 27023, CCUG 37669, CIP 106803, DSM 44075, HAMBI 2272, JCM 6372, M. obuense, Mycobacterium obuense, NCTC 10778, strain 4388, strain 47001
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.