node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
alc | ftsH2 | MOBUDSM44075_05289 | MOBUDSM44075_01038 | Allantoicase. | ATP-dependent zinc metalloprotease FtsH 2; Belongs to the AAA ATPase family. | 0.806 |
cheR2 | ftsH2 | MOBUDSM44075_03915 | MOBUDSM44075_01038 | Chemotaxis protein methyltransferase Cher2. | ATP-dependent zinc metalloprotease FtsH 2; Belongs to the AAA ATPase family. | 0.709 |
dnaN | ftsH2 | MOBUDSM44075_04714 | MOBUDSM44075_01038 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent zinc metalloprotease FtsH 2; Belongs to the AAA ATPase family. | 0.837 |
dnaN | recA | MOBUDSM44075_04714 | MOBUDSM44075_02851 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.980 |
ftsH2 | alc | MOBUDSM44075_01038 | MOBUDSM44075_05289 | ATP-dependent zinc metalloprotease FtsH 2; Belongs to the AAA ATPase family. | Allantoicase. | 0.806 |
ftsH2 | cheR2 | MOBUDSM44075_01038 | MOBUDSM44075_03915 | ATP-dependent zinc metalloprotease FtsH 2; Belongs to the AAA ATPase family. | Chemotaxis protein methyltransferase Cher2. | 0.709 |
ftsH2 | dnaN | MOBUDSM44075_01038 | MOBUDSM44075_04714 | ATP-dependent zinc metalloprotease FtsH 2; Belongs to the AAA ATPase family. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.837 |
ftsH2 | glpK_1 | MOBUDSM44075_01038 | MOBUDSM44075_01355 | ATP-dependent zinc metalloprotease FtsH 2; Belongs to the AAA ATPase family. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | 0.770 |
ftsH2 | glpK_2 | MOBUDSM44075_01038 | MOBUDSM44075_01704 | ATP-dependent zinc metalloprotease FtsH 2; Belongs to the AAA ATPase family. | Glycerol kinase; Belongs to the FGGY kinase family. | 0.770 |
ftsH2 | htpG | MOBUDSM44075_01038 | MOBUDSM44075_03098 | ATP-dependent zinc metalloprotease FtsH 2; Belongs to the AAA ATPase family. | Chaperone protein HtpG; Molecular chaperone. Has ATPase activity. | 0.861 |
ftsH2 | mpa | MOBUDSM44075_01038 | MOBUDSM44075_01507 | ATP-dependent zinc metalloprotease FtsH 2; Belongs to the AAA ATPase family. | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.718 |
ftsH2 | prcA | MOBUDSM44075_01038 | MOBUDSM44075_01514 | ATP-dependent zinc metalloprotease FtsH 2; Belongs to the AAA ATPase family. | Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.833 |
ftsH2 | prcB | MOBUDSM44075_01038 | MOBUDSM44075_01513 | ATP-dependent zinc metalloprotease FtsH 2; Belongs to the AAA ATPase family. | Proteasome subunit beta precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.833 |
ftsH2 | recA | MOBUDSM44075_01038 | MOBUDSM44075_02851 | ATP-dependent zinc metalloprotease FtsH 2; Belongs to the AAA ATPase family. | Protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.717 |
glpK_1 | ftsH2 | MOBUDSM44075_01355 | MOBUDSM44075_01038 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | ATP-dependent zinc metalloprotease FtsH 2; Belongs to the AAA ATPase family. | 0.770 |
glpK_1 | glpK_2 | MOBUDSM44075_01355 | MOBUDSM44075_01704 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | Glycerol kinase; Belongs to the FGGY kinase family. | 0.909 |
glpK_1 | mpa | MOBUDSM44075_01355 | MOBUDSM44075_01507 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | Proteasome-associated ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. | 0.990 |
glpK_1 | prcA | MOBUDSM44075_01355 | MOBUDSM44075_01514 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family. | 0.970 |
glpK_1 | prcB | MOBUDSM44075_01355 | MOBUDSM44075_01513 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. | Proteasome subunit beta precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family. | 0.970 |
glpK_2 | ftsH2 | MOBUDSM44075_01704 | MOBUDSM44075_01038 | Glycerol kinase; Belongs to the FGGY kinase family. | ATP-dependent zinc metalloprotease FtsH 2; Belongs to the AAA ATPase family. | 0.770 |