STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
zntRHTH-type transcriptional regulator ZntR. (131 aa)    
Predicted Functional Partners:
accD
Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta.
   
  0.850
dosT_1
Hypoxia sensor histidine kinase response regulator DosT.
  
 0.785
todS
Sensor histidine kinase TodS.
  
 0.785
cya_2
Adenylate cyclase; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
   
 0.774
KMO68061.1
Hypothetical protein.
  
 
 0.756
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.746
KMO81337.1
Histone H1-like nucleoprotein HC2.
  
 
 0.744
dnaJ_1
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.744
dnaJ_2
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...]
  
 
 0.744
cbpA
Curved DNA-binding protein.
  
 
 0.744
Your Current Organism:
Mycolicibacterium obuense
NCBI taxonomy Id: 1807
Other names: ATCC 27023, CCUG 37669, CIP 106803, DSM 44075, HAMBI 2272, JCM 6372, M. obuense, Mycobacterium obuense, NCTC 10778, strain 4388, strain 47001
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