STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nasFUroporphyrinogen-III C-methyltransferase. (561 aa)    
Predicted Functional Partners:
hemB
Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family.
 
 0.999
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 0.999
cysG
Siroheme synthase.
 
 
0.998
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.995
cobI
Precorrin-2 C(20)-methyltransferase; Belongs to the precorrin methyltransferase family.
  
 
 0.992
KMO76043.1
Hypothetical protein.
  
    0.969
KMO76044.1
Hypothetical protein.
  
    0.969
hemE
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.953
KMO82010.1
Bifunctional uroporphyrinogen-III synthetase/response regulator domain protein.
 
 
 0.947
cysNC_1
Bifunctional enzyme CysN/CysC; Catalyzes the synthesis of activated sulfate. Belongs to the APS kinase family.
  
  
 0.917
Your Current Organism:
Mycolicibacterium obuense
NCBI taxonomy Id: 1807
Other names: ATCC 27023, CCUG 37669, CIP 106803, DSM 44075, HAMBI 2272, JCM 6372, M. obuense, Mycobacterium obuense, NCTC 10778, strain 4388, strain 47001
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