STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KYH46027.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (213 aa)    
Predicted Functional Partners:
gyrB
DNA topoisomerase IV subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.999
ispH
4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family.
       0.773
KYH44057.1
DNA topoisomerase IV subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.693
KYH45466.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
   0.637
KYH43918.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
 
 0.590
KYH45982.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
 
 0.590
KYH45600.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
   0.545
KYH45602.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
   0.545
KYH44331.1
Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.531
KYH46029.1
Antibiotic ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.530
Your Current Organism:
Branchiibius sp. NY1634622
NCBI taxonomy Id: 1807500
Other names: B. sp. NY16-3462-2, Branchiibius sp. NY16-3462-2
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.