| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ARA74526.1 | ARA75823.1 | B5S52_00905 | B5S52_08040 | Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aminotransferase class IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.912 |
| ARA74526.1 | ilvA | B5S52_00905 | B5S52_01080 | Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. | PLP-dependent threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.829 |
| ARA74526.1 | ilvE | B5S52_00905 | B5S52_01070 | Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Branched chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.914 |
| ARA74526.1 | metL | B5S52_00905 | B5S52_00910 | Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional aspartate kinase/homoserine dehydrogenase II; Multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.990 |
| ARA74526.1 | thrA | B5S52_00905 | B5S52_03135 | Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional aspartokinase I/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.935 |
| ARA75823.1 | ARA74526.1 | B5S52_08040 | B5S52_00905 | Aminotransferase class IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.912 |
| ARA75823.1 | ARA78135.1 | B5S52_08040 | B5S52_20545 | Aminotransferase class IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.968 |
| ARA75823.1 | avtA | B5S52_08040 | B5S52_00360 | Aminotransferase class IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | Valine--pyruvate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.919 |
| ARA75823.1 | ilvA | B5S52_08040 | B5S52_01080 | Aminotransferase class IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | PLP-dependent threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.883 |
| ARA75823.1 | ilvD | B5S52_08040 | B5S52_01075 | Aminotransferase class IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. | 0.973 |
| ARA75823.1 | ilvE | B5S52_08040 | B5S52_01070 | Aminotransferase class IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | Branched chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.919 |
| ARA75823.1 | leuA | B5S52_08040 | B5S52_03460 | Aminotransferase class IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.968 |
| ARA75823.1 | metL | B5S52_08040 | B5S52_00910 | Aminotransferase class IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional aspartate kinase/homoserine dehydrogenase II; Multifunctional homodimeric enzyme that catalyzes the phosphorylation of aspartate to form aspartyl-4-phosphate as well as conversion of aspartate semialdehyde to homoserine; functions in a number of amino acid biosynthetic pathways; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.909 |
| ARA75823.1 | panB | B5S52_08040 | B5S52_05995 | Aminotransferase class IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.926 |
| ARA75823.1 | thrA | B5S52_08040 | B5S52_03135 | Aminotransferase class IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | Bifunctional aspartokinase I/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.909 |
| ARA78135.1 | ARA75823.1 | B5S52_20545 | B5S52_08040 | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Aminotransferase class IV; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.968 |
| ARA78135.1 | avtA | B5S52_20545 | B5S52_00360 | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Valine--pyruvate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.904 |
| ARA78135.1 | ilvD | B5S52_20545 | B5S52_01075 | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. | 0.964 |
| ARA78135.1 | ilvE | B5S52_20545 | B5S52_01070 | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Branched chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. | 0.968 |
| ARA78135.1 | leuA | B5S52_20545 | B5S52_03460 | 2-isopropylmalate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.900 |