Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ytfEIron-sulfur cluster repair di-iron protein; Di-iron-containing protein involved in the repair of iron- sulfur clusters damaged by oxidative and nitrosative stress conditions. (221 aa)    
Predicted Functional Partners:
hmp
Hypothetical protein; Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress; Belongs to the globin family. Two-domain flavohemoproteins subfamily.
  
  
 0.975
ARA76782.1
Hybrid-cluster NAD(P)-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.694
norV
Nitric oxide reductase; Anaerobic nitric oxide reductase; uses NADH to detoxify nitric oxide (NO), protecting several 4Fe-4S NO-sensitive enzymes. Has at least 2 reductase partners, only one of which (NorW, flavorubredoxin reductase) has been identified. NO probably binds to the di-iron center; electrons enter from the NorW at rubredoxin and are transferred sequentially to the FMN center and the di-iron center. Also able to function as an aerobic oxygen reductase; In the N-terminal section; belongs to the zinc metallo- hydrolase group 3 family.
  
  
 0.612
ARA77074.1
Tellurite resistance protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.591
nsrR
Transcriptional repressor NsrR; Nitric oxide-sensitive repressor of genes involved in protecting the cell against nitrosative stress. May require iron for activity.
 
  
 0.538
ARA77808.1
EamA family transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.454
hcp
Hydroxylamine reductase; Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O.
  
  
 0.453
ARA77607.1
With TehA confers resistance to tellurite; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.451
ARA76263.1
Nitrate reductase molybdenum cofactor assembly chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.433
copA
Cu+ exporting ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.432
Your Current Organism:
Pectobacterium brasiliense
NCBI taxonomy Id: 180957
Other names: CFBP 6617, Erwinia carotovora subsp. brasiliensis, LMG 21371, LMG:21371, NCPPB 4609, P. brasiliense, Pectobacterium brasiliense Portier et al. 2019, Pectobacterium brasiliensis, Pectobacterium carotovorum subsp. brasiliense, Pectobacterium carotovorum subsp. brasiliensis, strain 212
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