Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
fliTFlagellar biosynthesis protein FliT; Dual-function protein that regulates the transcription of class 2 flagellar operons and that also acts as an export chaperone for the filament-capping protein FliD. As a transcriptional regulator, acts as an anti-FlhDC factor; it directly binds FlhC, thus inhibiting the binding of the FlhC/FlhD complex to class 2 promoters, resulting in decreased expression of class 2 flagellar operons. As a chaperone, effects FliD transition to the membrane by preventing its premature polymerization, and by directing it to the export apparatus. (126 aa)    
Predicted Functional Partners:
ARA75906.1
Flagellar filament capping protein FliD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.865
fliS
Flagellar protein FliS; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.818
ARA78364.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.762
flhD
Flagellar transcriptional activator FlhD; Functions in complex with FlhC as a master transcriptional regulator that regulates transcription of several flagellar and non- flagellar operons by binding to their promoter region. Activates expression of class 2 flagellar genes, including fliA, which is a flagellum-specific sigma factor that turns on the class 3 genes. Also regulates genes whose products function in a variety of physiological pathways; Belongs to the FlhD family.
 
     0.761
fliH
Flagellar assembly protein FliH; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.753
ARA77106.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.739
rcsD
Phosphotransferase RcsD; Component of the Rcs signaling system, which controls transcription of numerous genes. RcsD is a phosphotransfer intermediate between the sensor kinase RcsC and the response regulator RcsB. It acquires a phosphoryl group from RcsC and transfers it to RcsB.
  
     0.738
ARA75511.1
Two-component sensor histidine kinase; Part of the GlrKR two-component signal transduction system involved in the regulation of glmY; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.731
ARA76235.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.719
ARA77134.1
Outer membrane assembly protein AsmA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.714
Your Current Organism:
Pectobacterium brasiliense
NCBI taxonomy Id: 180957
Other names: CFBP 6617, Erwinia carotovora subsp. brasiliensis, LMG 21371, LMG:21371, NCPPB 4609, P. brasiliense, Pectobacterium brasiliense Portier et al. 2019, Pectobacterium brasiliensis, Pectobacterium carotovorum subsp. brasiliense, Pectobacterium carotovorum subsp. brasiliensis, strain 212
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