STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANX04700.1Nitroreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)    
Predicted Functional Partners:
birA
Hypothetical protein; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon.
  
    0.661
ribB
3,4-dihydroxy-2-butanone-4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family.
 
 
 0.597
ANX04699.1
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.578
ANX04329.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
    0.547
cysG
Sirohydrochlorin ferrochelatase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
  
  
 0.532
ANX03165.1
Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.510
ANX04045.1
pimeloyl-CoA dehydrogenase large subunit; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
     0.502
ANX03386.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
     0.493
ANX05658.1
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.486
gltB
Catalyzes the formation of glutamate from glutamine and alpha-ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.476
Your Current Organism:
Immundisolibacter cernigliae
NCBI taxonomy Id: 1810504
Other names: ATCC TSD-58, DSM 103040, Gammaproteobacteria bacterium TR3.2, I. cernigliae, Immundisolibacter cernigliae Corteselli et al. 2017, strain TR3.2
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