node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AOW77333.1 | AOW77334.1 | A3Q34_10965 | A3Q34_10970 | Reactive intermediate/imine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.683 |
AOW77333.1 | gmk | A3Q34_10965 | A3Q34_10980 | Reactive intermediate/imine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.428 |
AOW77333.1 | ilvA | A3Q34_10965 | A3Q34_10875 | Reactive intermediate/imine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | PLP-dependent threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.538 |
AOW77333.1 | nnrE | A3Q34_10965 | A3Q34_09265 | Reactive intermediate/imine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] | 0.471 |
AOW77333.1 | ribD | A3Q34_10965 | A3Q34_13700 | Reactive intermediate/imine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.444 |
AOW77333.1 | rph | A3Q34_10965 | A3Q34_11540 | Reactive intermediate/imine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.499 |
AOW77333.1 | rpoZ | A3Q34_10965 | A3Q34_10975 | Reactive intermediate/imine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.454 |
AOW77333.1 | trmH | A3Q34_10965 | A3Q34_10960 | Reactive intermediate/imine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA (guanosine(18)-2'-O)-methyltransferase TrmH; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.494 |
AOW77334.1 | AOW77333.1 | A3Q34_10970 | A3Q34_10965 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Reactive intermediate/imine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.683 |
AOW77334.1 | gmk | A3Q34_10970 | A3Q34_10980 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.946 |
AOW77334.1 | rpoZ | A3Q34_10970 | A3Q34_10975 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.632 |
AOW77334.1 | trmH | A3Q34_10970 | A3Q34_10960 | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | tRNA (guanosine(18)-2'-O)-methyltransferase TrmH; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.659 |
gmk | AOW77333.1 | A3Q34_10980 | A3Q34_10965 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Reactive intermediate/imine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.428 |
gmk | AOW77334.1 | A3Q34_10980 | A3Q34_10970 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance. | 0.946 |
gmk | ribD | A3Q34_10980 | A3Q34_13700 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.508 |
gmk | rpoZ | A3Q34_10980 | A3Q34_10975 | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.954 |
ilvA | AOW77333.1 | A3Q34_10875 | A3Q34_10965 | PLP-dependent threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Reactive intermediate/imine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.538 |
nnrE | AOW77333.1 | A3Q34_09265 | A3Q34_10965 | Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] | Reactive intermediate/imine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.471 |
nnrE | trmH | A3Q34_09265 | A3Q34_10960 | Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] | tRNA (guanosine(18)-2'-O)-methyltransferase TrmH; Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.536 |
ribD | AOW77333.1 | A3Q34_13700 | A3Q34_10965 | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Reactive intermediate/imine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.444 |