OGI39771.1 protein (Muproteobacteria bacterium RBG166213)

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second shell of interactors

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Edges:

Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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[Homology]

Score

OGI39771.1

Plasmid maintenance system killer protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (96 aa)

Predicted Functional Partners:

A2140_08745

0.968

OGI40404.1

0.939

A2140_09635

0.920

OGI41246.1

0.811

OGI40163.1

0.781

Your Current Organism:

Muproteobacteria bacterium RBG166213

NCBI taxonomy Id: 1817756
Other names: C. Muproteobacteria bacterium RBG_16_62_13, Candidatus Muproteobacteria bacterium RBG_16_62_13

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A2140_08745	OGI39771.1	A2140_08745	A2140_08750	Hypothetical protein; Metagenomic; derived from metagenome: subsurface metagenome.	Plasmid maintenance system killer protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.968
A2140_08745	OGI40404.1	A2140_08745	A2140_05270	Hypothetical protein; Metagenomic; derived from metagenome: subsurface metagenome.	Addiction module antidote protein, HigA family; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.775
A2140_09635	OGI39771.1	A2140_09635	A2140_08750	Hypothetical protein; Too many ambiguous residues; Derived by automated computational analysis using gene prediction method: Protein Homology.	Plasmid maintenance system killer protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.920
OGI39771.1	A2140_08745	A2140_08750	A2140_08745	Plasmid maintenance system killer protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Metagenomic; derived from metagenome: subsurface metagenome.	0.968
OGI39771.1	A2140_09635	A2140_08750	A2140_09635	Plasmid maintenance system killer protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Too many ambiguous residues; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.920
OGI39771.1	OGI40163.1	A2140_08750	A2140_06905	Plasmid maintenance system killer protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Addiction module antidote protein, HigA family; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.781
OGI39771.1	OGI40404.1	A2140_08750	A2140_05270	Plasmid maintenance system killer protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Addiction module antidote protein, HigA family; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.939
OGI39771.1	OGI41246.1	A2140_08750	A2140_06250	Plasmid maintenance system killer protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Addiction module antidote protein, HigA family; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.811
OGI40163.1	OGI39771.1	A2140_06905	A2140_08750	Addiction module antidote protein, HigA family; Derived by automated computational analysis using gene prediction method: Protein Homology.	Plasmid maintenance system killer protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.781
OGI40163.1	OGI40404.1	A2140_06905	A2140_05270	Addiction module antidote protein, HigA family; Derived by automated computational analysis using gene prediction method: Protein Homology.	Addiction module antidote protein, HigA family; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.755
OGI40404.1	A2140_08745	A2140_05270	A2140_08745	Addiction module antidote protein, HigA family; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Metagenomic; derived from metagenome: subsurface metagenome.	0.775
OGI40404.1	OGI39771.1	A2140_05270	A2140_08750	Addiction module antidote protein, HigA family; Derived by automated computational analysis using gene prediction method: Protein Homology.	Plasmid maintenance system killer protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.939
OGI40404.1	OGI40163.1	A2140_05270	A2140_06905	Addiction module antidote protein, HigA family; Derived by automated computational analysis using gene prediction method: Protein Homology.	Addiction module antidote protein, HigA family; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.755
OGI40404.1	OGI41246.1	A2140_05270	A2140_06250	Addiction module antidote protein, HigA family; Derived by automated computational analysis using gene prediction method: Protein Homology.	Addiction module antidote protein, HigA family; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.723
OGI41246.1	OGI39771.1	A2140_06250	A2140_08750	Addiction module antidote protein, HigA family; Derived by automated computational analysis using gene prediction method: Protein Homology.	Plasmid maintenance system killer protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.811
OGI41246.1	OGI40404.1	A2140_06250	A2140_05270	Addiction module antidote protein, HigA family; Derived by automated computational analysis using gene prediction method: Protein Homology.	Addiction module antidote protein, HigA family; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.723

Network Stats

number of nodes:

10

number of edges:

29

average node degree:

5.8

avg. local clustering coefficient:

0.817

expected number of edges:

23

PPI enrichment p-value:

0.121

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
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Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016226

Iron-sulfur cluster assembly

5 of 16

2.07

2.85

1.11e-06

GO:0006790

Sulfur compound metabolic process

6 of 101

1.35

1.49

4.36e-05

GO:0044571

[2Fe-2S] cluster assembly

2 of 2

2.58

1.15

0.0079

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4681

Mixed, incl. Iron-sulfur cluster assembly, and Cysteine desulfurase activity

8 of 24

2.1

5.16

6.55e-13

CL:4685

Cysteine desulfurase activity, and SUF system FeS cluster assembly, SufBD

5 of 11

2.23

3.56

5.42e-08

CL:4689

SUF system FeS cluster assembly, SufBD, and Cysteine desulfurase

4 of 5

2.48

3.27

5.60e-07

CL:2850

tRNA thio-modification, and [2Fe-2S] cluster assembly

2 of 6

2.1

0.86

0.0248

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map04122

Sulfur relay system

3 of 38

1.47

0.82

0.0178

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:1990229

Iron-sulfur cluster assembly complex

2 of 2

2.58

1.08

0.0109

GOCC:0009536

Plastid

3 of 26

1.64

0.95

0.0109

GOCC:0005654

Nucleoplasm

2 of 9

1.92

0.89

0.0197

GOCC:0005759

Mitochondrial matrix

2 of 11

1.84

0.85

0.0232

GOCC:0043231

Intracellular membrane-bounded organelle

5 of 231

0.91

0.57

0.0187

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00266

Aminotransferase class-V

3 of 14

1.91

1.16

0.0055

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR000192

Aminotransferase class V domain

3 of 12

1.97

1.06

0.0094

IPR045595

SUF system FeS cluster assembly, SufBD, N-terminal

2 of 2

2.58

0.85

0.0290

IPR037284

SUF system FeS cluster assembly, SufBD superfamily

2 of 2

2.58

0.85

0.0290

IPR000825

SUF system FeS cluster assembly, SufBD

2 of 2

2.58

0.85

0.0290

IPR016454

Cysteine desulfurase

2 of 3

2.4

0.84

0.0290

(more ...)

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