STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nfoHypothetical protein; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin. (277 aa)    
Predicted Functional Partners:
OGD76817.1
Endonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.923
OGD78947.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
   
 
 0.607
OGD75309.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.565
OGD74970.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.558
OGD78213.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.557
OGD74741.1
Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.461
A2Y64_04530
Hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
    
   0.435
Your Current Organism:
Coatesbacteria bacterium RBG136614
NCBI taxonomy Id: 1817816
Other names: C. Coatesbacteria bacterium RBG_13_66_14, Candidatus Coatesbacteria bacterium RBG_13_66_14
Server load: low (24%) [HD]