OGE83160.1 protein (Delongbacteria bacterium GWF24014)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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[Homology]

Score

OGE83160.1

Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)

Predicted Functional Partners:

OGE83159.1

0.986

OGE82233.1

0.938

OGE81962.1

0.868

OGE83142.1

0.759

OGE81565.1

0.728

OGE82962.1

0.714

OGE83926.1

0.703

OGE85982.1

0.692

OGE85983.1

0.678

OGE84539.1

0.677

Your Current Organism:

Delongbacteria bacterium GWF24014

NCBI taxonomy Id: 1817817
Other names: C. Delongbacteria bacterium GWF2_40_14, Candidatus Delongbacteria bacterium GWF2_40_14

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OGE81565.1	OGE82962.1	A2Y39_07795	A2Y39_07145	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.846
OGE81565.1	OGE83142.1	A2Y39_07795	A2Y39_02065	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.937
OGE81565.1	OGE83160.1	A2Y39_07795	A2Y39_02160	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.728
OGE81962.1	OGE82233.1	A2Y39_07340	A2Y39_03990	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
OGE81962.1	OGE82962.1	A2Y39_07340	A2Y39_07145	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.860
OGE81962.1	OGE83160.1	A2Y39_07340	A2Y39_02160	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.868
OGE81962.1	OGE85982.1	A2Y39_07340	A2Y39_05860	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.862
OGE81962.1	OGE85983.1	A2Y39_07340	A2Y39_05865	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.862
OGE82233.1	OGE81962.1	A2Y39_03990	A2Y39_07340	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.999
OGE82233.1	OGE82962.1	A2Y39_03990	A2Y39_07145	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.458
OGE82233.1	OGE83160.1	A2Y39_03990	A2Y39_02160	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.938
OGE82962.1	OGE81565.1	A2Y39_07145	A2Y39_07795	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.846
OGE82962.1	OGE81962.1	A2Y39_07145	A2Y39_07340	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.860
OGE82962.1	OGE82233.1	A2Y39_07145	A2Y39_03990	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.458
OGE82962.1	OGE83142.1	A2Y39_07145	A2Y39_02065	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.846
OGE82962.1	OGE83159.1	A2Y39_07145	A2Y39_02155	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.476
OGE82962.1	OGE83160.1	A2Y39_07145	A2Y39_02160	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.714
OGE82962.1	OGE84539.1	A2Y39_07145	A2Y39_01960	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Zinc ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.888
OGE82962.1	OGE85982.1	A2Y39_07145	A2Y39_05860	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.424
OGE82962.1	OGE85983.1	A2Y39_07145	A2Y39_05865	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.424

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Network Stats

number of nodes:

7

number of edges:

18

average node degree:

5.14

avg. local clustering coefficient:

0.914

expected number of edges:

6

PPI enrichment p-value:

0.000115

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0044205

De novo UMP biosynthetic process

8 of 10

2.64

7.85

1.99e-16

GO:0009112

Nucleobase metabolic process

6 of 23

2.16

4.47

1.57e-10

GO:0006207

De novo pyrimidine nucleobase biosynthetic process

4 of 5

2.64

3.99

2.88e-08

GO:0055086

Nucleobase-containing small molecule metabolic process

10 of 169

1.51

3.09

3.26e-13

GO:0000256

Allantoin catabolic process

2 of 3

2.57

1.72

0.00068

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004088

Carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity

2 of 3

2.57

0.93

0.0205

GO:0051537

2 iron, 2 sulfur cluster binding

2 of 12

1.96

0.76

0.0370

GO:0046872

Metal ion binding

6 of 515

0.81

0.48

0.0283

GO:0003824

Catalytic activity

11 of 2433

0.4

0.29

0.0205

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

10 of 1601

0.54

0.42

0.0019

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1515

Pyrimidine biosynthesis, and Allantoin catabolic process

9 of 16

2.49

8.16

4.96e-18

CL:1518

Pyrimidine biosynthesis

7 of 10

2.59

6.68

4.82e-14

CL:1520

De novo pyrimidine nucleobase biosynthetic process, and Carbamoyl-phosphate synthase L chain, ATP binding domain

3 of 5

2.52

2.34

4.21e-05

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00240

Pyrimidine metabolism

9 of 99

1.7

3.77

7.87e-13

map00250

Alanine, aspartate and glutamate metabolism

3 of 34

1.69

1.35

0.0013

map01100

Metabolic pathways

11 of 1698

0.55

0.49

4.97e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0665

Pyrimidine biosynthesis

7 of 10

2.59

6.85

2.00e-14

KW-0001

2Fe-2S

2 of 6

2.26

1.13

0.0078

KW-0055

Arginine biosynthesis

2 of 9

2.09

1.06

0.0102

KW-0285

Flavoprotein

2 of 18

1.79

0.86

0.0210

KW-0479

Metal-binding

4 of 214

1.01

0.61

0.0206

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF10418

Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B

2 of 3

2.57

0.92

0.0211

PF00970

Oxidoreductase FAD-binding domain

2 of 3

2.57

0.92

0.0211

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