OGF12301.1 protein (Edwardsbacteria bacterium GWE25412)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

OGF12301.1

Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (283 aa)

Predicted Functional Partners:

OGF12302.1

0.946

OGF12630.1

0.943

OGF12300.1

0.916

OGF12297.1

0.775

OGF12299.1

0.775

OGF12629.1

0.775

OGF12384.1

0.775

OGF12386.1

0.775

OGF12387.1

0.775

OGF10165.1

0.775

Your Current Organism:

Edwardsbacteria bacterium GWE25412

NCBI taxonomy Id: 1817850
Other names: C. Edwardsbacteria bacterium GWE2_54_12, Candidatus Edwardsbacteria bacterium GWE2_54_12

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OGF10165.1	OGF12297.1	A3K15_11920	A3K15_00320	Methylaspartate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.785
OGF10165.1	OGF12299.1	A3K15_11920	A3K15_00330	Methylaspartate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.785
OGF10165.1	OGF12300.1	A3K15_11920	A3K15_00340	Methylaspartate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.785
OGF10165.1	OGF12301.1	A3K15_11920	A3K15_00345	Methylaspartate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.775
OGF10165.1	OGF12302.1	A3K15_11920	A3K15_00350	Methylaspartate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.785
OGF10165.1	OGF12384.1	A3K15_11920	A3K15_00810	Methylaspartate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.785
OGF10165.1	OGF12386.1	A3K15_11920	A3K15_00820	Methylaspartate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.785
OGF10165.1	OGF12387.1	A3K15_11920	A3K15_00825	Methylaspartate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.785
OGF10165.1	OGF12629.1	A3K15_11920	A3K15_00335	Methylaspartate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.785
OGF10165.1	OGF12630.1	A3K15_11920	A3K15_00355	Methylaspartate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.785
OGF12297.1	OGF10165.1	A3K15_00320	A3K15_11920	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methylaspartate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.785
OGF12297.1	OGF12299.1	A3K15_00320	A3K15_00330	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.946
OGF12297.1	OGF12301.1	A3K15_00320	A3K15_00345	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.775
OGF12297.1	OGF12302.1	A3K15_00320	A3K15_00350	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.777
OGF12297.1	OGF12386.1	A3K15_00320	A3K15_00820	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.777
OGF12297.1	OGF12387.1	A3K15_00320	A3K15_00825	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.780
OGF12297.1	OGF12629.1	A3K15_00320	A3K15_00335	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.946
OGF12297.1	OGF12630.1	A3K15_00320	A3K15_00355	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.780
OGF12299.1	OGF10165.1	A3K15_00330	A3K15_11920	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Methylaspartate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.785
OGF12299.1	OGF12297.1	A3K15_00330	A3K15_00320	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.946

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Network Stats

number of nodes:

11

number of edges:

34

average node degree:

6.18

avg. local clustering coefficient:

0.897

expected number of edges:

11

PPI enrichment p-value:

1.75e-08

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

11 of 103

1.65

3.92

1.99e-15

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

10 of 51

1.91

5.24

7.18e-16

GO:0019843

rRNA binding

9 of 41

1.96

5.15

1.50e-14

GO:0003723

RNA binding

10 of 112

1.57

3.32

2.71e-13

GO:0000049

tRNA binding

4 of 28

1.77

1.86

8.24e-05

GO:0003676

Nucleic acid binding

11 of 630

0.86

0.94

6.10e-08

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

10 of 53

1.89

5.27

2.19e-16

GO:0044391

Ribosomal subunit

3 of 13

1.98

1.87

0.00016

GO:0015935

Small ribosomal subunit

2 of 6

2.14

1.35

0.0027

GO:0005622

Intracellular anatomical structure

11 of 1511

0.48

0.41

0.00016

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:158

Ribosome

11 of 52

1.94

5.97

1.41e-18

CL:160

Ribosome

10 of 47

1.94

5.62

7.41e-17

CL:162

Ribosome

8 of 32

2.01

5.07

1.81e-13

CL:164

Ribosome

6 of 25

2.0

3.8

1.67e-09

CL:165

rRNA-binding, and Signal sequence binding

5 of 19

2.04

3.29

6.92e-08

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

mdn03010

Ribosome

10 of 49

1.93

5.54

6.70e-17

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0022626

Cytosolic ribosome

7 of 25

2.06

4.57

2.20e-11

GOCC:0044391

Ribosomal subunit

7 of 27

2.03

4.48

2.34e-11

GOCC:0005840

Ribosome

8 of 46

1.86

4.07

1.18e-11

GOCC:0022627

Cytosolic small ribosomal subunit

4 of 10

2.22

3.07

6.58e-07

GOCC:0022625

Cytosolic large ribosomal subunit

3 of 15

1.92

1.79

0.00021

(more ...)

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0699

rRNA-binding

9 of 36

2.01

5.62

1.65e-15

KW-0689

Ribosomal protein

10 of 52

1.9

5.29

2.64e-16

KW-0820

tRNA-binding

3 of 16

1.89

1.62

0.00048

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