close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OGF12321.13-methyl-2-oxobutanoate dehydrogenase subunit VorB; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (412 aa)    
Predicted Functional Partners:
OGF12320.1
2-oxoglutarate oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.998
OGF12319.1
2-oxoacid:ferredoxin oxidoreductase subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.994
OGF10612.1
2-oxoacid:ferredoxin oxidoreductase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.982
OGF11628.1
Pyruvate ferredoxin oxidoreductase; Catalyzes the formation of acetyl-CoA from pyruvate and coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.981
OGF12499.1
2-oxoacid ferredoxin oxidoreductase; Catalyzes the coenzyme A-dependent decarboxylation of 2-oxoacids, such as pyruvate and 2-oxoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.976
OGF10611.1
2-oxoglutarate ferredoxin oxidoreductase subunit gamma; Catalyzes the ferredoxin-dependent oxidative decarboxylation 2-oxoglutarate forming succinyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.959
OGF12322.1
Tungsten formylmethanofuran dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.933
porA
Pyruvate ferredoxin oxidoreductase; Too many ambiguous residues; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 0.931
OGF12501.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
0.907
OGF10964.1
Indolepyruvate oxidoreductase subunit beta; Involved in the incorporation of exogenous aryl acids in the biosynthesis of aromatic amino acids: catalysis of the ferredoxin-dependent oxidative decarboxylation of arylpyruvates; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.904
Your Current Organism:
Edwardsbacteria bacterium GWE25412
NCBI taxonomy Id: 1817850
Other names: C. Edwardsbacteria bacterium GWE2_54_12, Candidatus Edwardsbacteria bacterium GWE2_54_12
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.