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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OGF11754.1Two-component system response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)    
Predicted Functional Partners:
OGF11381.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 0.972
OGF12568.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.971
OGF12652.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.964
OGF11085.1
Two-component sensor histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.940
OGF12605.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 
  0.925
A3K15_11085
Cysteine desulfurase NifS; Frameshifted; too many ambiguous residues; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.924
OGF09792.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 0.912
OGF11378.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 0.886
OGF09616.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 0.883
OGF10048.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 0.867
Your Current Organism:
Edwardsbacteria bacterium GWE25412
NCBI taxonomy Id: 1817850
Other names: C. Edwardsbacteria bacterium GWE2_54_12, Candidatus Edwardsbacteria bacterium GWE2_54_12
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