OGF11103.1 protein (Edwardsbacteria bacterium GWE25412)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

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Textmining

[Homology]

Score

OGF11103.1

Phosphate ABC transporter, permease protein PstA; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)

Predicted Functional Partners:

OGF10971.1

0.991

OGF11104.1

0.981

OGF10972.1

0.977

OGF10970.1

0.975

OGF10276.1

0.966

OGF09984.1

0.966

OGF12766.1

0.962

OGF09981.1

0.959

OGF09985.1

0.945

OGF09982.1

0.920

Your Current Organism:

Edwardsbacteria bacterium GWE25412

NCBI taxonomy Id: 1817850
Other names: C. Edwardsbacteria bacterium GWE2_54_12, Candidatus Edwardsbacteria bacterium GWE2_54_12

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OGF09981.1	OGF09982.1	A3K15_10910	A3K15_10915	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphate ABC transporter permease subunit PstC; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.987
OGF09981.1	OGF09984.1	A3K15_10910	A3K15_10930	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.927
OGF09981.1	OGF09985.1	A3K15_10910	A3K15_10935	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphate transport system regulatory protein PhoU; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.528
OGF09981.1	OGF10276.1	A3K15_10910	A3K15_10925	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.962
OGF09981.1	OGF10970.1	A3K15_10910	A3K15_07495	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphate transport system regulatory protein PhoU; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.600
OGF09981.1	OGF10971.1	A3K15_10910	A3K15_07500	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.857
OGF09981.1	OGF10972.1	A3K15_10910	A3K15_07510	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphate ABC transporter permease subunit PstC; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.959
OGF09981.1	OGF11103.1	A3K15_10910	A3K15_07505	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphate ABC transporter, permease protein PstA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.959
OGF09982.1	OGF09981.1	A3K15_10915	A3K15_10910	Phosphate ABC transporter permease subunit PstC; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.987
OGF09982.1	OGF09984.1	A3K15_10915	A3K15_10930	Phosphate ABC transporter permease subunit PstC; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.987
OGF09982.1	OGF09985.1	A3K15_10915	A3K15_10935	Phosphate ABC transporter permease subunit PstC; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphate transport system regulatory protein PhoU; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.723
OGF09982.1	OGF10276.1	A3K15_10915	A3K15_10925	Phosphate ABC transporter permease subunit PstC; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.993
OGF09982.1	OGF10970.1	A3K15_10915	A3K15_07495	Phosphate ABC transporter permease subunit PstC; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphate transport system regulatory protein PhoU; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.739
OGF09982.1	OGF10971.1	A3K15_10915	A3K15_07500	Phosphate ABC transporter permease subunit PstC; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.974
OGF09982.1	OGF11103.1	A3K15_10915	A3K15_07505	Phosphate ABC transporter permease subunit PstC; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphate ABC transporter, permease protein PstA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.920
OGF09982.1	OGF11104.1	A3K15_10915	A3K15_07515	Phosphate ABC transporter permease subunit PstC; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.911
OGF09982.1	OGF12766.1	A3K15_10915	A3K15_00075	Phosphate ABC transporter permease subunit PstC; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.892
OGF09984.1	OGF09981.1	A3K15_10930	A3K15_10910	Phosphate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.927
OGF09984.1	OGF09982.1	A3K15_10930	A3K15_10915	Phosphate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphate ABC transporter permease subunit PstC; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.987
OGF09984.1	OGF09985.1	A3K15_10930	A3K15_10935	Phosphate ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphate transport system regulatory protein PhoU; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.944

page 1 of 5

Network Stats

number of nodes:

11

number of edges:

51

average node degree:

9.27

avg. local clustering coefficient:

0.941

expected number of edges:

18

PPI enrichment p-value:

1.52e-10

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0019941

Modification-dependent protein catabolic process

2 of 2

3.03

1.54

0.0053

GO:0010498

Proteasomal protein catabolic process

2 of 2

3.03

1.54

0.0053

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000502

Proteasome complex

2 of 5

2.64

1.78

0.0021

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:1106

Proteasomal protein catabolic process, and ThiF family

2 of 5

2.64

1.15

0.0196

CL:687

FtsH Extracellular, and Prohibitin homologues

2 of 6

2.56

1.14

0.0196

CL:3005

Mixed, incl. Acetyltransferase (GNAT) domain, and Putative zinc- or iron-chelating domain

2 of 6

2.56

1.14

0.0196

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-1236975

Antigen processing-Cross presentation

2 of 11

2.29

1.79

0.0016

MAP-983169

Class I MHC mediated antigen processing & presentation

2 of 15

2.16

1.75

0.0016

MAP-1280218

Adaptive Immune System

2 of 15

2.16

1.75

0.0016

MAP-168256

Immune System

2 of 54

1.6

1.17

0.0075

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0000502

Proteasome complex

2 of 17

2.1

0.98

0.0312

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00244

Prohibitin homologues

2 of 3

2.86

2.02

0.00095

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