node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A2W00_13835 | OGF13155.1 | A2W00_13835 | A2W00_13840 | Hypothetical protein; Metagenomic; derived from metagenome: subsurface metagenome. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.991 |
A2W00_13835 | OGF13156.1 | A2W00_13835 | A2W00_13845 | Hypothetical protein; Metagenomic; derived from metagenome: subsurface metagenome. | 3-deoxy-8-phosphooctulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family. | 0.991 |
A2W00_13835 | OGF15275.1 | A2W00_13835 | A2W00_06725 | Hypothetical protein; Metagenomic; derived from metagenome: subsurface metagenome. | Hypothetical protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.871 |
A2W00_13835 | OGF15277.1 | A2W00_13835 | A2W00_06735 | Hypothetical protein; Metagenomic; derived from metagenome: subsurface metagenome. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.814 |
A2W00_13835 | OGF15279.1 | A2W00_13835 | A2W00_06745 | Hypothetical protein; Metagenomic; derived from metagenome: subsurface metagenome. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.764 |
A2W00_13835 | kdsB | A2W00_13835 | A2W00_13855 | Hypothetical protein; Metagenomic; derived from metagenome: subsurface metagenome. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.944 |
A2W00_13835 | lpxD | A2W00_13835 | A2W00_06755 | Hypothetical protein; Metagenomic; derived from metagenome: subsurface metagenome. | UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.782 |
A2W00_13835 | lpxK | A2W00_13835 | A2W00_06720 | Hypothetical protein; Metagenomic; derived from metagenome: subsurface metagenome. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.866 |
A2W00_13835 | pyrG | A2W00_13835 | A2W00_13850 | Hypothetical protein; Metagenomic; derived from metagenome: subsurface metagenome. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.874 |
OGF13155.1 | A2W00_13835 | A2W00_13840 | A2W00_13835 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Metagenomic; derived from metagenome: subsurface metagenome. | 0.991 |
OGF13155.1 | OGF13156.1 | A2W00_13840 | A2W00_13845 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-deoxy-8-phosphooctulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family. | 0.986 |
OGF13155.1 | OGF15275.1 | A2W00_13840 | A2W00_06725 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. | 0.779 |
OGF13155.1 | OGF15277.1 | A2W00_13840 | A2W00_06735 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.474 |
OGF13155.1 | OGF15279.1 | A2W00_13840 | A2W00_06745 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. | 0.475 |
OGF13155.1 | kdsB | A2W00_13840 | A2W00_13855 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-deoxy-D-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. | 0.954 |
OGF13155.1 | lpxD | A2W00_13840 | A2W00_06755 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily. | 0.464 |
OGF13155.1 | lpxK | A2W00_13840 | A2W00_06720 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tetraacyldisaccharide 4'-kinase; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). | 0.569 |
OGF13155.1 | pyrG | A2W00_13840 | A2W00_13850 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.789 |
OGF13156.1 | A2W00_13835 | A2W00_13845 | A2W00_13835 | 3-deoxy-8-phosphooctulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family. | Hypothetical protein; Metagenomic; derived from metagenome: subsurface metagenome. | 0.991 |
OGF13156.1 | OGF13155.1 | A2W00_13845 | A2W00_13840 | 3-deoxy-8-phosphooctulonate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the KdsA family. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.986 |