STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (495 aa)    
Predicted Functional Partners:
OGG05393.1
Anthranilate/aminodeoxychorismate synthase component II; TrpG; with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine; TrpG provides the glutamine amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology.
 0.999
trpD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 0.999
trpC
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family.
 0.999
trpF
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family.
 
 
 0.986
OGG05406.1
Imidazole glycerol phosphate synthase subunit HisF; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the HisA/HisF family.
 
  
 0.797
guaA
Hypothetical protein; Catalyzes the synthesis of GMP from XMP.
 
    
 0.788
OGG05394.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.773
hisI
phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.
 
    0.735
hisC
Histidinol-phosphate transaminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
 
 0.660
OGG05196.1
Dihydropteroate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.659
Your Current Organism:
Glassbacteria bacterium RIFCSPLOWO212FULL5811
NCBI taxonomy Id: 1817867
Other names: C. Glassbacteria bacterium RIFCSPLOWO2_12_FULL_58_11, Candidatus Glassbacteria bacterium RIFCSPLOWO2_12_FULL_58_11
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