STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiLThiamine-phosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (342 aa)    
Predicted Functional Partners:
OGG01056.1
Nucleoside-diphosphate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NDK family.
     
 0.763
OGG01057.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial histone-like protein family.
       0.752
OGG05327.1
Bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.701
OGG04726.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
    
 0.649
A3F83_16760
Hypothetical protein; Metagenomic; derived from metagenome: subsurface metagenome.
       0.609
sucD
succinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
       0.608
A3F83_00845
PtrB; oligopeptidase that cleaves peptide bonds following arginine and lysine residues; incomplete; too short partial abutting assembly gap; missing start; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
     
 0.584
OGG01268.1
Secondary thiamine-phosphate synthase enzyme; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.584
OGG02123.1
Phosphomethylpyrimidine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.554
ribBA
Bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.536
Your Current Organism:
Glassbacteria bacterium RIFCSPLOWO212FULL5811
NCBI taxonomy Id: 1817867
Other names: C. Glassbacteria bacterium RIFCSPLOWO2_12_FULL_58_11, Candidatus Glassbacteria bacterium RIFCSPLOWO2_12_FULL_58_11
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.