OGH97653.1 protein (Margulisbacteria bacterium GWD239127)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

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Score

OGH97653.1

Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (365 aa)

Predicted Functional Partners:

OGH96361.1

0.794

OGH95173.1

0.788

OGH97376.1

0.785

OGH95172.1

0.784

OGH97151.1

0.776

OGH97658.1

0.769

OGH95529.1

0.745

OGH97726.1

0.653

OGH94714.1

0.652

OGH97241.1

0.619

Your Current Organism:

Margulisbacteria bacterium GWD239127

NCBI taxonomy Id: 1817871
Other names: C. Margulisbacteria bacterium GWD2_39_127, Candidatus Margulisbacteria bacterium GWD2_39_127

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OGH94714.1	OGH97241.1	A2X43_10625	A2X43_08765	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Adenine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.870
OGH94714.1	OGH97653.1	A2X43_10625	A2X43_14040	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.652
OGH94714.1	OGH97658.1	A2X43_10625	A2X43_14065	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.652
OGH95172.1	OGH95173.1	A2X43_01155	A2X43_01160	Crossover junction endodeoxyribonuclease RuvC; Derived by automated computational analysis using gene prediction method: Protein Homology.	Holliday junction DNA helicase RuvA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
OGH95172.1	OGH95529.1	A2X43_01155	A2X43_07485	Crossover junction endodeoxyribonuclease RuvC; Derived by automated computational analysis using gene prediction method: Protein Homology.	Excinuclease ABC subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.815
OGH95172.1	OGH96361.1	A2X43_01155	A2X43_04340	Crossover junction endodeoxyribonuclease RuvC; Derived by automated computational analysis using gene prediction method: Protein Homology.	Holliday junction DNA helicase RuvB; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.993
OGH95172.1	OGH97151.1	A2X43_01155	A2X43_08270	Crossover junction endodeoxyribonuclease RuvC; Derived by automated computational analysis using gene prediction method: Protein Homology.	Excinuclease ABC subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.821
OGH95172.1	OGH97376.1	A2X43_01155	A2X43_13695	Crossover junction endodeoxyribonuclease RuvC; Derived by automated computational analysis using gene prediction method: Protein Homology.	Excinuclease ABC subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.820
OGH95172.1	OGH97653.1	A2X43_01155	A2X43_14040	Crossover junction endodeoxyribonuclease RuvC; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.784
OGH95172.1	OGH97658.1	A2X43_01155	A2X43_14065	Crossover junction endodeoxyribonuclease RuvC; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.784
OGH95173.1	OGH95172.1	A2X43_01160	A2X43_01155	Holliday junction DNA helicase RuvA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Crossover junction endodeoxyribonuclease RuvC; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
OGH95173.1	OGH95529.1	A2X43_01160	A2X43_07485	Holliday junction DNA helicase RuvA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Excinuclease ABC subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.848
OGH95173.1	OGH96361.1	A2X43_01160	A2X43_04340	Holliday junction DNA helicase RuvA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Holliday junction DNA helicase RuvB; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.999
OGH95173.1	OGH97151.1	A2X43_01160	A2X43_08270	Holliday junction DNA helicase RuvA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Excinuclease ABC subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.840
OGH95173.1	OGH97376.1	A2X43_01160	A2X43_13695	Holliday junction DNA helicase RuvA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Excinuclease ABC subunit A; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.837
OGH95173.1	OGH97653.1	A2X43_01160	A2X43_14040	Holliday junction DNA helicase RuvA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.788
OGH95173.1	OGH97658.1	A2X43_01160	A2X43_14065	Holliday junction DNA helicase RuvA; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.821
OGH95529.1	OGH95172.1	A2X43_07485	A2X43_01155	Excinuclease ABC subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology.	Crossover junction endodeoxyribonuclease RuvC; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.815
OGH95529.1	OGH95173.1	A2X43_07485	A2X43_01160	Excinuclease ABC subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology.	Holliday junction DNA helicase RuvA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.848
OGH95529.1	OGH96361.1	A2X43_07485	A2X43_04340	Excinuclease ABC subunit C; Derived by automated computational analysis using gene prediction method: Protein Homology.	Holliday junction DNA helicase RuvB; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.857

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

26

average node degree:

4.73

avg. local clustering coefficient:

0.941

expected number of edges:

11

PPI enrichment p-value:

4.42e-05

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006260

DNA replication

3 of 29

1.48

0.7

0.0344

GO:0006259

DNA metabolic process

5 of 116

1.1

0.61

0.0302

GO:0090304

Nucleic acid metabolic process

6 of 272

0.81

0.47

0.0344

GO:0046483

Heterocycle metabolic process

8 of 503

0.66

0.41

0.0302

GO:1901360

Organic cyclic compound metabolic process

8 of 524

0.65

0.4

0.0302

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030894

Replisome

4 of 9

2.11

2.58

5.87e-06

GO:0043590

Bacterial nucleoid

2 of 6

1.98

1.23

0.0041

GO:0032991

Protein-containing complex

5 of 156

0.97

0.76

0.0024

GO:0005622

Intracellular anatomical structure

8 of 961

0.38

0.27

0.0415

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3344

Mixed, incl. Smr domain, and RuvB-like P-loop domain

5 of 5

2.46

3.87

3.04e-08

CL:723

3-5 exonuclease activity, and DNA damage sensor activity

3 of 10

1.94

1.41

0.0016

CL:733

Bacterial nucleoid, and Rad50/SbcC-type AAA domain

2 of 5

2.06

0.9

0.0205

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03030

DNA replication

3 of 25

1.54

0.92

0.0114

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005694

Chromosome

4 of 24

1.68

1.57

0.00034

GOCC:0043590

Bacterial nucleoid

2 of 8

1.86

0.72

0.0428

GOCC:0030894

Replisome

2 of 9

1.81

0.71

0.0428

GOCC:0043229

Intracellular organelle

5 of 272

0.73

0.41

0.0457

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