STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiEThiamine-phosphate diphosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). (225 aa)    
Predicted Functional Partners:
OGL55401.1
Bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
thiC
Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
 
 0.995
thiG
Thiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S.
 
 0.992
OGL55404.1
Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.974
OGL52623.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
      0.899
OGL51438.1
Sugar kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
  0.876
OGL52692.1
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofH; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.838
OGL54333.1
7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit CofG; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.838
OGL54009.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
  0.717
OGL55464.1
Adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.703
Your Current Organism:
Schekmanbacteria bacterium RIFCSPLOWO212FULL3815
NCBI taxonomy Id: 1817883
Other names: C. Schekmanbacteria bacterium RIFCSPLOWO2_12_FULL_38_15, Candidatus Schekmanbacteria bacterium RIFCSPLOWO2_12_FULL_38_15
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.