OGJ99356.1 protein (Raymondbacteria bacterium RIFOXYC2FULL5021)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

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[Homology]

Score

OGJ99356.1

Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (719 aa)

Predicted Functional Partners:

OGJ96603.1

0.952

OGJ96920.1

0.948

OGJ99181.1

0.912

OGJ96083.1

0.901

OGJ97231.1

0.823

OGJ96613.1

0.798

OGJ97682.1

0.742

OGJ98771.1

0.739

OGJ95898.1

0.718

OGJ99376.1

0.718

Your Current Organism:

Raymondbacteria bacterium RIFOXYC2FULL5021

NCBI taxonomy Id: 1817889
Other names: C. Raymondbacteria bacterium RIFOXYC2_FULL_50_21, Candidatus Raymondbacteria bacterium RIFOXYC2_FULL_50_21

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
OGJ95898.1	OGJ96603.1	A2453_01085	A2453_06330	Flagellar motor switch protein FliM; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.973
OGJ95898.1	OGJ96613.1	A2453_01085	A2453_06390	Flagellar motor switch protein FliM; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.921
OGJ95898.1	OGJ96920.1	A2453_01085	A2453_04775	Flagellar motor switch protein FliM; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.738
OGJ95898.1	OGJ97682.1	A2453_01085	A2453_09545	Flagellar motor switch protein FliM; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.976
OGJ95898.1	OGJ98771.1	A2453_01085	A2453_09810	Flagellar motor switch protein FliM; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.835
OGJ95898.1	OGJ99181.1	A2453_01085	A2453_07095	Flagellar motor switch protein FliM; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.955
OGJ95898.1	OGJ99356.1	A2453_01085	A2453_13590	Flagellar motor switch protein FliM; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.718
OGJ95898.1	OGJ99376.1	A2453_01085	A2453_13695	Flagellar motor switch protein FliM; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.780
OGJ96083.1	OGJ96603.1	A2453_08350	A2453_06330	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.930
OGJ96083.1	OGJ96613.1	A2453_08350	A2453_06390	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.733
OGJ96083.1	OGJ96920.1	A2453_08350	A2453_04775	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.948
OGJ96083.1	OGJ97231.1	A2453_08350	A2453_01305	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.671
OGJ96083.1	OGJ97682.1	A2453_08350	A2453_09545	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.667
OGJ96083.1	OGJ98771.1	A2453_08350	A2453_09810	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.623
OGJ96083.1	OGJ99181.1	A2453_08350	A2453_07095	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.995
OGJ96083.1	OGJ99356.1	A2453_08350	A2453_13590	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.901
OGJ96083.1	OGJ99376.1	A2453_08350	A2453_13695	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.475
OGJ96603.1	OGJ95898.1	A2453_06330	A2453_01085	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Flagellar motor switch protein FliM; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.973
OGJ96603.1	OGJ96083.1	A2453_06330	A2453_08350	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.930
OGJ96603.1	OGJ96613.1	A2453_06330	A2453_06390	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.998

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Network Stats

number of nodes:

11

number of edges:

55

average node degree:

10

avg. local clustering coefficient:

1

expected number of edges:

28

PPI enrichment p-value:

2.57e-06

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006412

Translation

10 of 102

1.49

2.84

8.60e-12

GO:0009987

Cellular process

11 of 1718

0.31

0.25

0.0204

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003735

Structural constituent of ribosome

9 of 52

1.74

3.82

2.54e-12

GO:0019843

rRNA binding

4 of 42

1.48

1.21

0.0015

GO:0003723

RNA binding

5 of 107

1.17

0.95

0.0018

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005840

Ribosome

9 of 57

1.7

3.75

9.05e-13

GO:0015935

Small ribosomal subunit

2 of 8

1.9

1.15

0.0055

GO:0005622

Intracellular anatomical structure

11 of 1098

0.5

0.44

5.17e-05

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:22043294

(2011) Gut microbiome metagenomics analysis suggests a functional model for the development of autoimmunity for type 1 diabetes.

3 of 8

2.07

1.68

0.00051

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:133

Structural constituent of ribosome

9 of 58

1.69

3.67

1.85e-12

CL:122

Ribosome, and Translation regulator activity

10 of 81

1.59

3.35

7.71e-13

CL:171

Mixed, incl. Translation regulation, and Nucleotide-binding alpha-beta plait domain superfamily

4 of 6

2.32

3.15

6.41e-07

CL:134

rRNA-binding, and EFG, domain V

6 of 31

1.79

3.01

2.57e-08

CL:136

rRNA-binding

5 of 25

1.8

2.59

7.95e-07

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03010

Ribosome

9 of 57

1.7

3.74

1.00e-12

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005840

Ribosome

9 of 45

1.8

4.24

3.02e-13

GOCC:0022626

Cytosolic ribosome

2 of 12

1.72

0.84

0.0221

GOCC:0044391

Ribosomal subunit

2 of 17

1.57

0.71

0.0366

GOCC:0005622

Intracellular

11 of 1069

0.51

0.44

8.89e-05

GOCC:0110165

Cellular anatomical entity

11 of 1701

0.31

0.26

0.0123

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0689

Ribosomal protein

9 of 54

1.72

3.83

1.05e-12

KW-0699

rRNA-binding

4 of 39

1.51

1.43

0.00036

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