STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
radADNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (454 aa)    
Predicted Functional Partners:
recA
Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
  
 0.803
tilS
tRNA lysidine(34) synthetase TilS; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.
  
    0.796
recX
Hypothetical protein; Modulates RecA activity; Belongs to the RecX family.
  
  
 0.792
OIP99149.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the helicase family. UvrD subfamily.
  
  
 0.758
OIP97403.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
  
 0.726
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.570
OIP96735.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.540
OIP97408.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.492
OIP97407.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.491
pheT
phenylalanine--tRNA ligase subunit beta; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
 
  
 0.489
Your Current Organism:
Wirthbacteria bacterium CG2305411
NCBI taxonomy Id: 1817892
Other names: C. Wirthbacteria bacterium CG2_30_54_11, Candidatus Wirthbacteria bacterium CG2_30_54_11
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.