STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thi4Ribose 1,5-bisphosphate isomerase; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur. (255 aa)    
Predicted Functional Partners:
OIN98500.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
OIN98499.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.757
OIN98498.1
Riboflavin synthase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.644
thiC
Phosphomethylpyrimidine synthase; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family.
  
  
 0.500
OIN98502.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.440
OIN98496.1
DNA methylase N-4; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the N(4)/N(6)-methyltransferase family.
       0.430
OIN98497.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.430
Your Current Organism:
Desantisbacteria bacterium CG1023846
NCBI taxonomy Id: 1817893
Other names: C. Desantisbacteria bacterium CG1_02_38_46, Candidatus Desantisbacteria bacterium CG1_02_38_46
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