CVT24_006116 protein (Panaeolus cyanescens) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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Score

CVT24_006116

AB hydrolase-1 domain-containing protein. (752 aa)

Predicted Functional Partners:

CVT24_008435

0.669

CVT24_010564

0.532

CVT24_011825

0.470

CVT24_004276

0.422

CVT24_012510

0.400

Your Current Organism:

Panaeolus cyanescens

NCBI taxonomy Id: 181874
Other names: Copelandia cyanescens, P. cyanescens

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CVT24_004276	CVT24_006116	A0A409VA48	A0A409VDI2	Uncharacterized protein.	AB hydrolase-1 domain-containing protein.	0.422
CVT24_004276	CVT24_010564	A0A409VA48	A0A409YYV5	Uncharacterized protein.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.521
CVT24_006116	CVT24_004276	A0A409VDI2	A0A409VA48	AB hydrolase-1 domain-containing protein.	Uncharacterized protein.	0.422
CVT24_006116	CVT24_008435	A0A409VDI2	A0A409VBK8	AB hydrolase-1 domain-containing protein.	Uncharacterized protein.	0.669
CVT24_006116	CVT24_010564	A0A409VDI2	A0A409YYV5	AB hydrolase-1 domain-containing protein.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.532
CVT24_006116	CVT24_011825	A0A409VDI2	A0A409YNQ5	AB hydrolase-1 domain-containing protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.470
CVT24_006116	CVT24_012510	A0A409VDI2	A0A409YK51	AB hydrolase-1 domain-containing protein.	CBM1 domain-containing protein.	0.400
CVT24_008435	CVT24_006116	A0A409VBK8	A0A409VDI2	Uncharacterized protein.	AB hydrolase-1 domain-containing protein.	0.669
CVT24_010564	CVT24_004276	A0A409YYV5	A0A409VA48	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.521
CVT24_010564	CVT24_006116	A0A409YYV5	A0A409VDI2	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	AB hydrolase-1 domain-containing protein.	0.532
CVT24_010564	CVT24_011825	A0A409YYV5	A0A409YNQ5	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.994
CVT24_011825	CVT24_006116	A0A409YNQ5	A0A409VDI2	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	AB hydrolase-1 domain-containing protein.	0.470
CVT24_011825	CVT24_010564	A0A409YNQ5	A0A409YYV5	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.994
CVT24_012510	CVT24_006116	A0A409YK51	A0A409VDI2	CBM1 domain-containing protein.	AB hydrolase-1 domain-containing protein.	0.400

Network Stats

number of nodes:

11

number of edges:

15

average node degree:

2.73

avg. local clustering coefficient:

0.859

expected number of edges:

10

PPI enrichment p-value:

0.105

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0032957

Inositol trisphosphate metabolic process

4 of 5

3.24

4.19

2.40e-08

GO:0070266

Necroptotic process

4 of 13

2.83

3.59

2.27e-07

GO:0006066

Alcohol metabolic process

5 of 291

1.58

1.61

0.00014

GO:0052746

Inositol phosphorylation

2 of 3

3.16

1.54

0.0017

GO:0032958

Inositol phosphate biosynthetic process

2 of 14

2.5

0.97

0.0167

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000825

Inositol tetrakisphosphate 6-kinase activity

4 of 4

3.34

4.61

4.39e-09

GO:0051766

Inositol trisphosphate kinase activity

4 of 9

2.99

4.26

1.49e-08

GO:0003993

Acid phosphatase activity

3 of 7

2.97

2.88

5.66e-06

GO:0102732

myo-inositol-1,2,3,4,6-heptakisphosphate 5-kinase activity

2 of 2

3.34

1.83

0.00051

GO:0052726

inositol-1,3,4-trisphosphate 5-kinase activity

2 of 2

3.34

1.83

0.00051

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:30075

Acid phosphatase activity, and Alkaline phosphatase activity

6 of 14

2.97

6.68

3.23e-13

CL:30076

Acid phosphatase activity, and Phosphodiesterase I activity

4 of 7

3.1

4.32

1.27e-08

CL:38050

Inositol trisphosphate kinase activity, and Inositol tetrakisphosphate phosphatase activity

4 of 17

2.71

3.62

1.72e-07

CL:38074

Inositol phosphorylation, and Inositol tetrakisphosphate 5-kinase activity

3 of 5

3.12

2.98

3.89e-06

CL:30089

Alkaline phosphatase activity, and Acid phosphatase activity

2 of 7

2.8

1.41

0.0028

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00730

Thiamine metabolism

4 of 21

2.62

3.84

5.24e-08

map00740

Riboflavin metabolism

3 of 19

2.54

2.8

5.30e-06

map00562

Inositol phosphate metabolism

5 of 169

1.81

2.66

5.39e-07

map04070

Phosphatidylinositol signaling system

4 of 181

1.68

1.89

4.16e-05

map01100

Metabolic pathways

11 of 3242

0.87

0.96

5.24e-08

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-1483249

Inositol phosphate metabolism

5 of 70

2.19

3.28

1.94e-07

MAP-196819

Vitamin B1 (thiamin) metabolism

2 of 5

2.94

1.47

0.0022

MAP-1855191

Synthesis of IPs in the nucleus

2 of 7

2.8

1.41

0.0028

MAP-1855167

Synthesis of pyrophosphates in the cytosol

2 of 10

2.64

1.3

0.0042

MAP-196849

Metabolism of water-soluble vitamins and cofactors

3 of 192

1.53

0.79

0.0228

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00149

Calcineurin-like phosphoesterase

3 of 14

2.67

2.15

0.00011

PF05770

Inositol 1,3,4-trisphosphate 5/6-kinase ATP-grasp domain

2 of 2

3.34

1.6

0.0013

PF03770

Inositol polyphosphate kinase

2 of 9

2.69

1.15

0.0081

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