STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CVT24_007047DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (1079 aa)    
Predicted Functional Partners:
CVT24_003845
3'-5' exonuclease domain-containing protein.
  
 0.997
CVT24_000755
3'-5' exonuclease domain-containing protein.
  
 0.997
CVT24_006893
3'-5' exonuclease domain-containing protein.
  
 0.997
CVT24_000821
3'-5' exonuclease domain-containing protein.
  
 0.997
CVT24_009330
RMI1_N domain-containing protein.
    
 0.996
CVT24_011313
Uncharacterized protein.
   
 0.969
CVT24_005728
Uncharacterized protein.
  
 0.966
CVT24_012794
Uncharacterized protein.
  
 0.966
CVT24_007674
Uncharacterized protein.
    
 0.965
CVT24_002708
Protein kinase domain-containing protein.
    
 0.965
Your Current Organism:
Panaeolus cyanescens
NCBI taxonomy Id: 181874
Other names: Copelandia cyanescens, P. cyanescens
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