CVT24_012539 protein (Panaeolus cyanescens) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

CVT24_012539

Uncharacterized protein. (771 aa)

Predicted Functional Partners:

CVT24_002562

0.804

CVT24_005079

0.639

CVT24_002142

0.482

CVT24_008768

0.479

CVT24_004840

0.479

CVT24_010933

0.479

CVT24_011097

0.472

CVT24_004633

0.463

CVT24_004283

0.459

CVT24_004850

0.459

Your Current Organism:

Panaeolus cyanescens

NCBI taxonomy Id: 181874
Other names: Copelandia cyanescens, P. cyanescens

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... functional annotations:

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CVT24_002142	CVT24_002562	A0A409YI09	A0A409YTW9	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	Uncharacterized protein.	0.479
CVT24_002142	CVT24_005079	A0A409YI09	A0A409YB06	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	Uncharacterized protein.	0.479
CVT24_002142	CVT24_012539	A0A409YI09	A0A409X0S6	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	Uncharacterized protein.	0.482
CVT24_002562	CVT24_002142	A0A409YTW9	A0A409YI09	Uncharacterized protein.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.479
CVT24_002562	CVT24_005079	A0A409YTW9	A0A409YB06	Uncharacterized protein.	Uncharacterized protein.	0.434
CVT24_002562	CVT24_011097	A0A409YTW9	A0A409YG32	Uncharacterized protein.	EGF-like domain-containing protein.	0.505
CVT24_002562	CVT24_012539	A0A409YTW9	A0A409X0S6	Uncharacterized protein.	Uncharacterized protein.	0.804
CVT24_004283	CVT24_004850	A0A409VA46	A0A409VQB9	Uncharacterized protein.	Uncharacterized protein.	0.478
CVT24_004283	CVT24_012539	A0A409VA46	A0A409X0S6	Uncharacterized protein.	Uncharacterized protein.	0.459
CVT24_004633	CVT24_012539	A0A409YSM0	A0A409X0S6	Uncharacterized protein.	Uncharacterized protein.	0.463
CVT24_004840	CVT24_012539	A0A409VQB0	A0A409X0S6	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Uncharacterized protein.	0.479
CVT24_004850	CVT24_004283	A0A409VQB9	A0A409VA46	Uncharacterized protein.	Uncharacterized protein.	0.478
CVT24_004850	CVT24_012539	A0A409VQB9	A0A409X0S6	Uncharacterized protein.	Uncharacterized protein.	0.459
CVT24_005079	CVT24_002142	A0A409YB06	A0A409YI09	Uncharacterized protein.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.479
CVT24_005079	CVT24_002562	A0A409YB06	A0A409YTW9	Uncharacterized protein.	Uncharacterized protein.	0.434
CVT24_005079	CVT24_012539	A0A409YB06	A0A409X0S6	Uncharacterized protein.	Uncharacterized protein.	0.639
CVT24_008768	CVT24_012539	A0A409VB37	A0A409X0S6	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Uncharacterized protein.	0.479
CVT24_010933	CVT24_012539	A0A409WDE1	A0A409X0S6	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Uncharacterized protein.	0.479
CVT24_011097	CVT24_002562	A0A409YG32	A0A409YTW9	EGF-like domain-containing protein.	Uncharacterized protein.	0.505
CVT24_011097	CVT24_012539	A0A409YG32	A0A409X0S6	EGF-like domain-containing protein.	Uncharacterized protein.	0.472

page 1 of 2

Network Stats

number of nodes:

9

number of edges:

9

average node degree:

2

avg. local clustering coefficient:

0.893

expected number of edges:

9

PPI enrichment p-value:

0.557

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005544

Calcium-dependent phospholipid binding

2 of 4

2.87

1.22

0.0087

GO:0008289

Lipid binding

3 of 118

1.58

0.72

0.0420

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030126

COPI vesicle coat

2 of 9

2.52

1.04

0.0169

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:9127

COPI vesicle coat

2 of 6

2.7

0.99

0.0212

CL:3051

Mixed, incl. Annexin, and Protein of unknown function DUF4646

2 of 6

2.7

0.99

0.0212

CL:2958

Mostly uncharacterized, incl. Regulation of actomyosin contractile ring contraction, and Serine-type endopeptidase inhibitor activity

3 of 87

1.71

0.89

0.0212

CL:356

Proteasome

2 of 43

1.84

0.74

0.0463

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-597592

Post-translational protein modification

5 of 725

1.01

0.54

0.0457

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0030663

COPI-coated vesicle membrane

2 of 9

2.52

0.99

0.0206

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0041

Annexin

2 of 2

3.17

1.93

0.00055

KW-0931

ER-Golgi transport

2 of 11

2.43

1.41

0.0036

KW-0333

Golgi apparatus

2 of 20

2.17

1.22

0.0070

KW-0653

Protein transport

2 of 64

1.67

0.71

0.0480

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF04053

Coatomer WD associated region

2 of 2

3.17

1.55

0.0024

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR037104

Annexin superfamily

2 of 2

3.17

1.29

0.0067

IPR018502

Annexin repeat

2 of 2

3.17

1.29

0.0067

IPR011048

Cytochrome cd1-nitrite reductase-like, haem d1 domain superfamily

2 of 3

3.0

1.29

0.0067

IPR006692

Coatomer, WD associated region

2 of 2

3.17

1.29

0.0067

IPR001464

Annexin

2 of 2

3.17

1.29

0.0067

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00335

Annexin repeats

2 of 2

3.17

1.84

0.00077

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