CVT24_000942 protein (Panaeolus cyanescens) - STRING interaction network

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second shell of interactors

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Known Interactions

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Predicted Interactions

gene neighborhood

gene fusions

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protein homology

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[Homology]

Score

CVT24_000942

Phosphoinositide phospholipase C. (542 aa)

Predicted Functional Partners:

CVT24_009297

0.940

CVT24_007895

0.930

CVT24_010530

0.918

CVT24_006200

0.915

CVT24_007550

0.914

CVT24_010610

0.910

CVT24_005939

0.908

CVT24_003964

0.905

CVT24_009341

0.903

CVT24_000474

0.902

Your Current Organism:

Panaeolus cyanescens

NCBI taxonomy Id: 181874
Other names: Copelandia cyanescens, P. cyanescens

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CVT24_000474	CVT24_000942	A0A409VDC2	A0A409YCJ3	SAC domain-containing protein.	Phosphoinositide phospholipase C.	0.902
CVT24_000474	CVT24_003964	A0A409VDC2	A0A409Y6R6	SAC domain-containing protein.	PI3K/PI4K domain-containing protein.	0.939
CVT24_000474	CVT24_005939	A0A409VDC2	A0A409V8Y7	SAC domain-containing protein.	CDP-diacylglycerol--inositol 3-phosphatidyltransferase.	0.924
CVT24_000474	CVT24_006200	A0A409VDC2	A0A409VZY9	SAC domain-containing protein.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.978
CVT24_000474	CVT24_009297	A0A409VDC2	A0A409Y834	SAC domain-containing protein.	PIPK domain-containing protein.	0.947
CVT24_000474	CVT24_009341	A0A409VDC2	A0A409Y8A9	SAC domain-containing protein.	Phosphatidylinositol 3-kinase VPS34.	0.937
CVT24_000474	CVT24_010530	A0A409VDC2	A0A409YYL0	SAC domain-containing protein.	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family.	0.953
CVT24_000474	CVT24_010610	A0A409VDC2	A0A409YLZ0	SAC domain-containing protein.	SAC domain-containing protein.	0.948
CVT24_000942	CVT24_000474	A0A409YCJ3	A0A409VDC2	Phosphoinositide phospholipase C.	SAC domain-containing protein.	0.902
CVT24_000942	CVT24_003964	A0A409YCJ3	A0A409Y6R6	Phosphoinositide phospholipase C.	PI3K/PI4K domain-containing protein.	0.905
CVT24_000942	CVT24_005939	A0A409YCJ3	A0A409V8Y7	Phosphoinositide phospholipase C.	CDP-diacylglycerol--inositol 3-phosphatidyltransferase.	0.908
CVT24_000942	CVT24_006200	A0A409YCJ3	A0A409VZY9	Phosphoinositide phospholipase C.	Uncharacterized protein; Belongs to the PI3/PI4-kinase family.	0.915
CVT24_000942	CVT24_007550	A0A409YCJ3	A0A409W4J8	Phosphoinositide phospholipase C.	Inositol-1-monophosphatase.	0.914
CVT24_000942	CVT24_007895	A0A409YCJ3	A0A409VZL4	Phosphoinositide phospholipase C.	Kinase; Belongs to the inositol phosphokinase (IPK) family.	0.930
CVT24_000942	CVT24_009297	A0A409YCJ3	A0A409Y834	Phosphoinositide phospholipase C.	PIPK domain-containing protein.	0.940
CVT24_000942	CVT24_009341	A0A409YCJ3	A0A409Y8A9	Phosphoinositide phospholipase C.	Phosphatidylinositol 3-kinase VPS34.	0.903
CVT24_000942	CVT24_010530	A0A409YCJ3	A0A409YYL0	Phosphoinositide phospholipase C.	PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family.	0.918
CVT24_000942	CVT24_010610	A0A409YCJ3	A0A409YLZ0	Phosphoinositide phospholipase C.	SAC domain-containing protein.	0.910
CVT24_003964	CVT24_000474	A0A409Y6R6	A0A409VDC2	PI3K/PI4K domain-containing protein.	SAC domain-containing protein.	0.939
CVT24_003964	CVT24_000942	A0A409Y6R6	A0A409YCJ3	PI3K/PI4K domain-containing protein.	Phosphoinositide phospholipase C.	0.905

page 1 of 4

Network Stats

number of nodes:

11

number of edges:

53

average node degree:

9.64

avg. local clustering coefficient:

0.962

expected number of edges:

12

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016491

Oxidoreductase activity

7 of 587

0.74

0.41

0.0498

Reference Publications (PubMed)

publication

(year) title

count in network

strength

signal

false discovery rate

PMID:25423265

(2015) Hydroxycinnamic Acid Degradation, a Broadly Conserved Trait, Protects Ralstonia solanacearum from Chemical Plant Defenses and Contributes to Root Colonization and Virulence.

8 of 11

2.53

7.22

1.62e-15

PMID:31392803

(2019) Involvement of a PadR regulator PrhP on virulence of Ralstonia solanacearum by controlling detoxification of phenolic acids and type III secretion system.

3 of 18

1.89

1.09

0.0074

PMID:32283875

(2020) Breast Milk, a Source of Beneficial Microbes and Associated Benefits for Infant Health.

2 of 2

2.67

1.04

0.0129

PMID:23298573

(2013) Characterization and genomic analysis of kraft lignin biodegradation by the beta-proteobacterium Cupriavidus basilensis B-8.

2 of 5

2.27

0.8

0.0339

PMID:17959646

(2007) A comprehensive set of plasmids for vanillate- and xylose-inducible gene expression in Caulobacter crescentus.

2 of 5

2.27

0.8

0.0339

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:2543

Mixed, incl. Degradation of aromatic compounds, and Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site

8 of 28

2.12

5.27

4.94e-13

CL:2555

Mixed, incl. Aromatic-ring-hydroxylating dioxygenase, 2Fe-2S-binding site, and enoyl-CoA hydratase activity

5 of 5

2.67

4.54

2.33e-09

CL:2205

Mixed, incl. Fatty acid metabolic process, and Valine, leucine and isoleucine degradation

9 of 197

1.33

2.04

4.65e-09

CL:2573

Benzoate degradation

3 of 13

2.03

1.58

0.00080

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

rso01220

Degradation of aromatic compounds

3 of 33

1.63

1.06

0.0060

rso00362

Benzoate degradation

3 of 39

1.55

1.03

0.0060

rso00627

Aminobenzoate degradation

2 of 16

1.76

0.88

0.0187

rso01120

Microbial metabolism in diverse environments

5 of 272

0.93

0.67

0.0062

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