STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CVT24_002190Pyruvate carboxyltransferase domain-containing protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (566 aa)    
Predicted Functional Partners:
CVT24_003872
3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 
 0.971
CVT24_000856
Beta-glucosidase; Belongs to the glycosyl hydrolase 3 family.
  
 0.959
CVT24_004752
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
   
 0.929
CVT24_008325
Thiolase_N domain-containing protein.
  
 
 0.926
CVT24_003025
Acetyl-coenzyme A synthetase.
  
 
 0.925
CVT24_000437
Succinate--CoA ligase [ADP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
  
 
 0.924
CVT24_006083
Aldedh domain-containing protein.
   
 
 0.923
CVT24_009741
Malate synthase; Belongs to the malate synthase family.
     
 0.921
CVT24_003753
AcetylCoA_hyd_C domain-containing protein.
    
 0.916
CVT24_000878
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.911
Your Current Organism:
Panaeolus cyanescens
NCBI taxonomy Id: 181874
Other names: Copelandia cyanescens, P. cyanescens
Server load: low (16%) [HD]