node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HCW_01795 | HCW_01805 | HCW_01795 | HCW_01805 | Radical SAM domain-containing protein; COG0731 Fe-S oxidoreductases. | Flagellin B; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | 0.632 |
HCW_01795 | HCW_01810 | HCW_01795 | HCW_01810 | Radical SAM domain-containing protein; COG0731 Fe-S oxidoreductases. | COG2604 Uncharacterized protein conserved in bacteria. | 0.544 |
HCW_01795 | obgE | HCW_01795 | HCW_08270 | Radical SAM domain-containing protein; COG0731 Fe-S oxidoreductases. | GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.676 |
HCW_01795 | pcm | HCW_01795 | HCW_07765 | Radical SAM domain-containing protein; COG0731 Fe-S oxidoreductases. | COG2518 Protein-L-isoaspartate carboxylmethyltransferase. | 0.611 |
HCW_01795 | topA | HCW_01795 | HCW_01800 | Radical SAM domain-containing protein; COG0731 Fe-S oxidoreductases. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.849 |
HCW_01805 | HCW_01795 | HCW_01805 | HCW_01795 | Flagellin B; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | Radical SAM domain-containing protein; COG0731 Fe-S oxidoreductases. | 0.632 |
HCW_01805 | HCW_01810 | HCW_01805 | HCW_01810 | Flagellin B; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | COG2604 Uncharacterized protein conserved in bacteria. | 0.911 |
HCW_01805 | topA | HCW_01805 | HCW_01800 | Flagellin B; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.652 |
HCW_01810 | HCW_01795 | HCW_01810 | HCW_01795 | COG2604 Uncharacterized protein conserved in bacteria. | Radical SAM domain-containing protein; COG0731 Fe-S oxidoreductases. | 0.544 |
HCW_01810 | HCW_01805 | HCW_01810 | HCW_01805 | COG2604 Uncharacterized protein conserved in bacteria. | Flagellin B; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | 0.911 |
HCW_01810 | topA | HCW_01810 | HCW_01800 | COG2604 Uncharacterized protein conserved in bacteria. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.494 |
obgE | HCW_01795 | HCW_08270 | HCW_01795 | GTPase CgtA; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Radical SAM domain-containing protein; COG0731 Fe-S oxidoreductases. | 0.676 |
pcm | HCW_01795 | HCW_07765 | HCW_01795 | COG2518 Protein-L-isoaspartate carboxylmethyltransferase. | Radical SAM domain-containing protein; COG0731 Fe-S oxidoreductases. | 0.611 |
topA | HCW_01795 | HCW_01800 | HCW_01795 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | Radical SAM domain-containing protein; COG0731 Fe-S oxidoreductases. | 0.849 |
topA | HCW_01805 | HCW_01800 | HCW_01805 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | Flagellin B; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. | 0.652 |
topA | HCW_01810 | HCW_01800 | HCW_01810 | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | COG2604 Uncharacterized protein conserved in bacteria. | 0.494 |