STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HCW_07300Hypothetical protein; COG0381 UDP-N-acetylglucosamine 2-epimerase. (388 aa)    
Predicted Functional Partners:
HCW_07295
N-acylneuraminate cytidylyltransferase; COG1083 CMP-N-acetylneuraminic acid synthetase.
 
  
 0.972
HCW_07265
flaA1 protein; COG1086 Predicted nucleoside-diphosphate sugar epimerases.
  
 
 0.952
HCW_07305
N-acetylneuraminic acid synthetase; COG2089 Sialic acid synthase.
 
  
 0.951
glmU
Glucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
    
 0.931
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
  
 
  0.907
HCW_06850
Viral A-type inclusion protein repeat protein.
  
  
 0.882
HCW_07290
Bifunctional alpha-2,3/-2,8-sialyltransferase.
  
    0.877
HCW_06090
COG1083 CMP-N-acetylneuraminic acid synthetase.
 
  
 0.824
lpxA
UDP-N-acetylglucosamine acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
    
  0.812
HCW_04930
UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase; COG0399 Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis; Belongs to the DegT/DnrJ/EryC1 family.
  
  
 0.802
Your Current Organism:
Helicobacter cetorum MIT007128
NCBI taxonomy Id: 182217
Other names: H. cetorum MIT 00-7128, Helicobacter cetorum MIT 00-7128, Helicobacter cetorum str. MIT 00-7128, Helicobacter cetorum strain MIT 00-7128, Helicobacter sp. MIT 00-7128
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