node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
OAP85425.1 | OAP86028.1 | A4H34_10075 | A4H34_02285 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | L-serine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.844 |
OAP85425.1 | glyA | A4H34_10075 | A4H34_06050 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.889 |
OAP85425.1 | ilvA | A4H34_10075 | A4H34_01620 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.829 |
OAP85425.1 | trpA | A4H34_10075 | A4H34_07575 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Prolipoprotein diacylglyceryl transferase; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.830 |
OAP85425.1 | trpB | A4H34_10075 | A4H34_07580 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.829 |
OAP85425.1 | trpC | A4H34_10075 | A4H34_07585 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Indole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. | 0.479 |
OAP85997.1 | OAP87142.1 | A4H34_02125 | A4H34_07590 | Anthranilate synthase component II; Aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. | Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
OAP85997.1 | trpA | A4H34_02125 | A4H34_07575 | Anthranilate synthase component II; Aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. | Prolipoprotein diacylglyceryl transferase; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.975 |
OAP85997.1 | trpB | A4H34_02125 | A4H34_07580 | Anthranilate synthase component II; Aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.951 |
OAP85997.1 | trpC | A4H34_02125 | A4H34_07585 | Anthranilate synthase component II; Aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. | Indole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. | 0.997 |
OAP85997.1 | trpD | A4H34_02125 | A4H34_08905 | Anthranilate synthase component II; Aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
OAP86028.1 | OAP85425.1 | A4H34_02285 | A4H34_10075 | L-serine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.844 |
OAP86028.1 | glyA | A4H34_02285 | A4H34_06050 | L-serine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.974 |
OAP86028.1 | ilvA | A4H34_02285 | A4H34_01620 | L-serine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.910 |
OAP86028.1 | trpA | A4H34_02285 | A4H34_07575 | L-serine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Prolipoprotein diacylglyceryl transferase; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.830 |
OAP87142.1 | OAP85997.1 | A4H34_07590 | A4H34_02125 | Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Anthranilate synthase component II; Aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.999 |
OAP87142.1 | trpA | A4H34_07590 | A4H34_07575 | Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Prolipoprotein diacylglyceryl transferase; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.996 |
OAP87142.1 | trpB | A4H34_07590 | A4H34_07580 | Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.990 |
OAP87142.1 | trpC | A4H34_07590 | A4H34_07585 | Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Indole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. | 0.999 |
OAP87142.1 | trpD | A4H34_07590 | A4H34_08905 | Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |