STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BcpA2-Methylisocitrate lyase, PEP mutase family. (250 aa)    
Predicted Functional Partners:
prpD
2-methylcitrate dehydratase.
 
  
 0.802
poxB
Pyruvate dehydrogenase (quinone); Belongs to the TPP enzyme family.
  
  
 0.725
glcB
Malate synthase; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
 
 0.724
YhdH
Putative quinone oxidoreductase, YhdH/YhfP family.
   
  
 0.716
SFM02776.1
Putative hydrolase.
   
    0.703
mshD
Mycothiol synthase; Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol.
   
    0.703
prpC
Citrate synthase; Belongs to the citrate synthase family.
 
 
 0.702
acn
Aconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
  
 0.695
gltA
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.625
CitA
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.625
Your Current Organism:
Nocardia asteroides
NCBI taxonomy Id: 1824
Other names: ATCC 19247, Actinomyces asteroides, Actinomyces eppinger, Actinomyces eppingeri, Asteroides asteroides, CCM 2754, CCUG 10073, CIP 104503, Cladothrix asteroides, DSM 43373, DSM 43757, Discomyces asteroides, IFO 15531, IMET 7547, JCM 3384, N. asteroides, NBRC 15531, NCTC 11293, NRRL B-3828, Oospora asteroides, Proactinomyces asteroides, Streptothrix eppingerii, Streptotrix asteroides
Server load: low (22%) [HD]