STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aceEPyruvate dehydrogenase E1 component; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (961 aa)    
Predicted Functional Partners:
lpd
Dihydrolipoamide dehydrogenase.
  
 
 0.983
bkdH
Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase).
  
 0.979
bkdF
Pyruvate dehydrogenase E1 component alpha subunit.
    
 0.952
pyk
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.944
pyc
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
    
 0.934
DlaT
2-oxoglutarate dehydrogenase E2 component.
 
 
 0.925
Tme
Malate dehydrogenase (oxaloacetate-decarboxylating).
    
 0.924
bkdG
Pyruvate dehydrogenase E1 component beta subunit.
     
 0.924
ppsA
Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
     
 0.913
LldD
L-lactate dehydrogenase (cytochrome).
     
 0.907
Your Current Organism:
Nocardia asteroides
NCBI taxonomy Id: 1824
Other names: ATCC 19247, Actinomyces asteroides, Actinomyces eppinger, Actinomyces eppingeri, Asteroides asteroides, CCM 2754, CCUG 10073, CIP 104503, Cladothrix asteroides, DSM 43373, DSM 43757, Discomyces asteroides, IFO 15531, IMET 7547, JCM 3384, N. asteroides, NBRC 15531, NCTC 11293, NRRL B-3828, Oospora asteroides, Proactinomyces asteroides, Streptothrix eppingerii, Streptotrix asteroides
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.