STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SFN08073.1Sigma-70, region 4. (394 aa)    
Predicted Functional Partners:
rpoB
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.733
BmrR_1
DNA-binding transcriptional regulator, MerR family.
  
 
 0.716
BmrR_2
DNA-binding transcriptional regulator, MerR family.
  
 
 0.716
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.707
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 0.683
rpoZ
DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
   
 
 0.669
SFN70062.1
Transcriptional regulator, CarD family.
   
 
 0.637
SFN43122.1
PAS domain S-box-containing protein.
  
 
 0.628
rbpA
RNA polymerase-binding protein; Binds to RNA polymerase (RNAP), stimulating transcription from principal, but not alternative sigma factor promoters. Belongs to the RNA polymerase-binding protein RbpA family.
    
 
 0.611
mraY
Phospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily.
       0.584
Your Current Organism:
Nocardia asteroides
NCBI taxonomy Id: 1824
Other names: ATCC 19247, Actinomyces asteroides, Actinomyces eppinger, Actinomyces eppingeri, Asteroides asteroides, CCM 2754, CCUG 10073, CIP 104503, Cladothrix asteroides, DSM 43373, DSM 43757, Discomyces asteroides, IFO 15531, IMET 7547, JCM 3384, N. asteroides, NBRC 15531, NCTC 11293, NRRL B-3828, Oospora asteroides, Proactinomyces asteroides, Streptothrix eppingerii, Streptotrix asteroides
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