STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
apeBUnannotated protein. (434 aa)    
Predicted Functional Partners:
GCA_000716895_02698
Unannotated protein.
       0.995
GCA_000716895_01257
Unannotated protein.
  
    0.977
arc
Unannotated protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
  
    0.975
trmL
Unannotated protein; Could methylate the ribose at the nucleotide 34 wobble position in tRNA; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.
       0.974
GCA_000716895_01243
Unannotated protein.
       0.974
trmI
Unannotated protein; Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA.
       0.974
dop
Unannotated protein.
       0.974
GCA_000716895_01249
Unannotated protein.
       0.974
pafA
Unannotated protein; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine.
       0.974
GCA_000716895_01258
Unannotated protein.
       0.974
Your Current Organism:
Rhodococcus rhodochrous
NCBI taxonomy Id: 1829
Other names: ATCC 13808, Bacterium mycoides roseum, CCUG 47165, CIP 104376, DSM 43241, Gordona rosea, IEGM 62, IFO 16069, IMET 7374, JCM 3202, LMG 5365, LMG:5365, NBRC 16069, NCIB 11147, NCIB:11147, NCTC 10210, NRRL B-16536, NRRL B-2149, R. rhodochrous, Rhodococcus rhodochrous isolate DY5, Rhodococcus rhodochrous isolate DY6, Rhodococcus rhodochrous str. J1, Rhodococcus roseus, Staphylococcus rhodochrous
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.