STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GCA_000716895_03643Unannotated protein. (207 aa)    
Predicted Functional Partners:
guaA
Unannotated protein; Catalyzes the synthesis of GMP from XMP.
    
 0.991
ndrR
Unannotated protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family.
  
    0.990
lytC_4
Unannotated protein.
  
 
 0.970
lexA_1
Unannotated protein; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
  
  
 0.955
guaB
Unannotated protein; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
  0.947
GCA_000716895_00741
Unannotated protein.
     
 0.938
GCA_000716895_01453
Unannotated protein.
  
  
 0.937
GCA_000716895_00773
Unannotated protein.
   
  0.927
GCA_000716895_05011
Unannotated protein.
    
 0.922
GCA_000716895_03096
Unannotated protein.
     
 0.920
Your Current Organism:
Rhodococcus rhodochrous
NCBI taxonomy Id: 1829
Other names: ATCC 13808, Bacterium mycoides roseum, CCUG 47165, CIP 104376, DSM 43241, Gordona rosea, IEGM 62, IFO 16069, IMET 7374, JCM 3202, LMG 5365, LMG:5365, NBRC 16069, NCIB 11147, NCIB:11147, NCTC 10210, NRRL B-16536, NRRL B-2149, R. rhodochrous, Rhodococcus rhodochrous isolate DY5, Rhodococcus rhodochrous isolate DY6, Rhodococcus rhodochrous str. J1, Rhodococcus roseus, Staphylococcus rhodochrous
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.