STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
glnR_2Unannotated protein. (135 aa)    
Predicted Functional Partners:
dnaJ_2
Unannotated protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...]
  
 
 0.999
GCA_000716895_04596
Unannotated protein.
  
  
 0.999
dnaK1_2
Unannotated protein; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.999
dnaJ_1
Unannotated protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK [...]
  
 
 0.986
GCA_000716895_02941
Unannotated protein.
   
  0.966
clpB_2
Unannotated protein; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family.
  
  
 0.965
hrcA
Unannotated protein; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons.
  
 
 0.950
GCA_000716895_00093
Unannotated protein.
    
 0.944
gltB_2
Unannotated protein.
    
 0.944
GCA_000716895_04668
Unannotated protein.
   
 0.935
Your Current Organism:
Rhodococcus rhodochrous
NCBI taxonomy Id: 1829
Other names: ATCC 13808, Bacterium mycoides roseum, CCUG 47165, CIP 104376, DSM 43241, Gordona rosea, IEGM 62, IFO 16069, IMET 7374, JCM 3202, LMG 5365, LMG:5365, NBRC 16069, NCIB 11147, NCIB:11147, NCTC 10210, NRRL B-16536, NRRL B-2149, R. rhodochrous, Rhodococcus rhodochrous isolate DY5, Rhodococcus rhodochrous isolate DY6, Rhodococcus rhodochrous str. J1, Rhodococcus roseus, Staphylococcus rhodochrous
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.