STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lepil_0551Unannotated protein. (618 aa)    
Predicted Functional Partners:
Lepil_0552
Unannotated protein.
 0.999
Lepil_0821
Unannotated protein.
  
 0.999
nuoI
Unannotated protein; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
  
 0.982
Lepil_2752
Unannotated protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions.
  
 0.982
Lepil_4027
Unannotated protein; Belongs to the monomeric-type IDH family.
  
 
 0.959
Lepil_2409
Unannotated protein.
  
 
 0.958
mdh
Unannotated protein; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
  
 
 0.953
topA
Unannotated protein; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...]
  
   0.947
Lepil_0049
Unannotated protein; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
    
   0.942
Lepil_1749
Unannotated protein.
  
 
 0.924
Your Current Organism:
Leptonema illini
NCBI taxonomy Id: 183
Other names: DSM 21528, L. illini, Leptospira illini, NCTC 11301, strain 3055
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.