STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKD97989.1AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)    
Predicted Functional Partners:
AKE00064.1
Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.701
trxC_2
Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family.
       0.622
AKD97987.1
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.607
AKD99382.1
AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.575
AKD97988.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.566
AKE00119.1
Isochorismatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.550
lexA
ArsR family transcriptional regulator; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
   
 
 0.452
lexA-2
LexA family transcriptional regulator; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.
   
 
 0.452
AKE00346.1
AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.449
AKD99241.1
NmrA family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.442
Your Current Organism:
Rhodococcus erythropolis
NCBI taxonomy Id: 1833
Other names: ATCC 4277, Arthrobacter hydrocarboglutamicus, Arthrobacter oxamicetus, Arthrobacter oxamicetus subsp. propiophenicolus, Arthrobacter paraffineus, Arthrobacter picolinophilus, Brevibacterium healii, Brevibacterium ketoglutamicum, Brevibacterium paraffinoliticum, CIP 104179, Corynebacterium alkanum, Corynebacterium aurantiacum, Corynebacterium humiferum, Corynebacterium sp. WS2071, Corynebacterium sp. WS2072, DSM 43066, IEGM 7, IFO 15567, JCM 20419, JCM 3201, LMG 5359, LMG:5359, Mycobacterium erythropolis, NBRC 15567, NCIB 11148, NCIB 9158, NCIB:11148, NCIB:9158, NCIMB 9158, NCTC 13021, NRRL B-16025, Nocardia calcarea, Nocardioides simplex ATCC 13260, Nocardioides simplex ATCC 19565, Nocardioides simplex ATCC 19566, R. erythropolis, Rhodococcus NI86/21, Rhodococcus sp. (strain NI86/21), Rhodococcus sp. ATCC 15108, Rhodococcus sp. ATCC 15961, Rhodococcus sp. ATCC 21035, Rhodococcus sp. BG43, Rhodococcus sp. BZ4, Rhodococcus sp. NCIB 9646, Rhodococcus sp. NI86/21, Rhodococcus sp. strain NI86/21, VKM Ac-858, strain N11
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.