STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AKE00049.1Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (314 aa)    
Predicted Functional Partners:
AKD96012.1
4-hydroxy-2-oxopentanoic acid aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 0.999
AKE01043.1
4-hyroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 0.999
AKE01042.1
2-keto-4-pentenoate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.978
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 0.962
leuA-2
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
  
 0.962
hsaE
2-keto-4-pentenoate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.944
AKD96578.1
Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family.
     
 0.931
ald_2
Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.
    
 0.909
geoB_2
Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.
    
 0.909
thcA
Aldehyde dehydrogenase; Degrades all aldehydes potentially generated by N dealkylation of thiocarbamates and may also participate in ethanolamine metabolism and further assimilation of degradation products by thiocarbamate-induced cytochrome P-450.
    
 0.909
Your Current Organism:
Rhodococcus erythropolis
NCBI taxonomy Id: 1833
Other names: ATCC 4277, Arthrobacter hydrocarboglutamicus, Arthrobacter oxamicetus, Arthrobacter oxamicetus subsp. propiophenicolus, Arthrobacter paraffineus, Arthrobacter picolinophilus, Brevibacterium healii, Brevibacterium ketoglutamicum, Brevibacterium paraffinoliticum, CIP 104179, Corynebacterium alkanum, Corynebacterium aurantiacum, Corynebacterium humiferum, Corynebacterium sp. WS2071, Corynebacterium sp. WS2072, DSM 43066, IEGM 7, IFO 15567, JCM 20419, JCM 3201, LMG 5359, LMG:5359, Mycobacterium erythropolis, NBRC 15567, NCIB 11148, NCIB 9158, NCIB:11148, NCIB:9158, NCIMB 9158, NCTC 13021, NRRL B-16025, Nocardia calcarea, Nocardioides simplex ATCC 13260, Nocardioides simplex ATCC 19565, Nocardioides simplex ATCC 19566, R. erythropolis, Rhodococcus NI86/21, Rhodococcus sp. (strain NI86/21), Rhodococcus sp. ATCC 15108, Rhodococcus sp. ATCC 15961, Rhodococcus sp. ATCC 21035, Rhodococcus sp. BG43, Rhodococcus sp. BZ4, Rhodococcus sp. NCIB 9646, Rhodococcus sp. NI86/21, Rhodococcus sp. strain NI86/21, VKM Ac-858, strain N11
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