STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OBF89504.1Type VII secretion AAA-ATPase EccA; Derived by automated computational analysis using gene prediction method: Protein Homology. (610 aa)    
Predicted Functional Partners:
OBF89507.1
Type VII secretion integral membrane protein EccD; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.923
OBF89505.1
Type VII secretion protein EccE; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.891
OBF89506.1
Type VII secretion-associated serine protease mycosin; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.886
glpK
Methyltransferase type 11; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
  0.756
prcA
Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1A family.
   
 0.723
prcB
Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. Belongs to the peptidase T1B family.
   
 0.723
htpG
Molecular chaperone HtpG; Molecular chaperone. Has ATPase activity.
    
 0.705
OBF89508.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.667
arc
Proteasome ATPase; ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis.
   
  0.661
OBF89487.1
Multidrug ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.653
Your Current Organism:
Mycobacterium sp. 85200251163SCH5372311
NCBI taxonomy Id: 1834097
Other names: M. sp. 852002-51163_SCH5372311, Mycobacterium sp. 852002-51163_SCH5372311
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.