STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OBB63746.1Dienelactone hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)    
Predicted Functional Partners:
OBB64465.1
Carboxymethylenebutenolidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.883
OBB65336.1
Carboxymethylenebutenolidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.826
OBB65322.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.740
OBB63744.1
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
       0.728
thyA
Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
     
 0.624
OBB63932.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.590
OBB68950.1
Bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.578
OBB65522.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.516
OBB69934.1
3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.514
OBB63741.1
Restriction endonuclease subunit S; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.462
Your Current Organism:
Mycobacterium sp. 85201450255SCH5639931
NCBI taxonomy Id: 1834112
Other names: M. sp. 852014-50255_SCH5639931, Mycobacterium sp. 852014-50255_SCH5639931
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