STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
OBF28174.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)    
Predicted Functional Partners:
OBF28172.1
Isoniazid-inducible protein iniC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.913
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.650
OBF41801.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.544
OBF28173.1
Isoniazid-inducible protein iniA; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.544
OBF36695.1
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.493
OBF29015.1
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.489
OBF28176.1
Molecular chaperone; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.461
OBF28175.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.452
OBF33872.1
Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family.
    
  0.446
OBF27200.1
Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family.
    
  0.446
Your Current Organism:
Mycobacterium sp. ACS1612
NCBI taxonomy Id: 1834117
Other names: M. sp. ACS1612
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.