STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
eisAcetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)    
Predicted Functional Partners:
OBH98122.1
Nicotinamidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.815
OBH95134.1
Enoyl-[acyl-carrier-protein] reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.813
OBH93868.1
16S/23S rRNA (cytidine-2'-O)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.813
OBH98476.1
Arabinosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.813
whiB
Transcriptional regulator; Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA.
   
  
 0.807
OBH88526.1
MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
  
 0.782
OBH90628.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.726
katG
Catalase/peroxidase HPI; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily.
      
 0.626
gyrB
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
      
 0.626
rpsL
30S ribosomal protein S12; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.
      
 0.621
Your Current Organism:
Mycobacterium sp. E2733
NCBI taxonomy Id: 1834138
Other names: M. sp. E2733
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