STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANU53333.2Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)    
Predicted Functional Partners:
A4V00_04390
Hypothetical protein; Incomplete; partial on complete genome; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.776
ANU53331.1
Acetolactate synthase, large subunit, biosynthetic type; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.774
ANU53332.1
Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
       0.598
ANU53335.2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.596
ANU53336.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.596
ilvD
Dihydroxy-acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family.
  
    0.452
ANU53338.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.449
Your Current Organism:
Hungateiclostridiaceae bacterium KB18
NCBI taxonomy Id: 1834198
Other names: H. bacterium KB18, Ruminiclostridium sp. KB18
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.